SNPs in 3′ UTR miRNA target sequences associated with individual drug susceptibility

E Rykova, N Ershov, I Damarov… - International Journal of …, 2022 - mdpi.com
The complementary interaction of microRNAs (miRNAs) with their binding sites in the 3′
untranslated regions (3′ UTRs) of target gene mRNAs represses translation, playing a …

[HTML][HTML] Secure transplantation by tissue purging using photodynamic therapy to eradicate malignant cells

S Moghassemi, A Dadashzadeh… - … of Photochemistry and …, 2022 - Elsevier
The field of photodynamic therapy (PDT) for treating various malignant neoplasms has been
given researchers' attention due to its ability to be a selective and minimally invasive cancer …

A diagnostic model for sepsis-induced acute lung injury using a consensus machine learning approach and its therapeutic implications

Y Zheng, J Wang, Z Ling, J Zhang, Y Zeng… - Journal of Translational …, 2023 - Springer
Background A significant proportion of septic patients with acute lung injury (ALI) are
recognized late due to the absence of an efficient diagnostic test, leading to the postponed …

Nanomanipulation of ligand nanogeometry modulates integrin/clathrin-mediated adhesion and endocytosis of stem cells

B Yin, Q Zhang, J Yan, Y Huang, C Li, J Chen… - Nano Letters, 2023 - ACS Publications
Nanosubstrate engineering can be a biomechanical approach for modulating stem cell
differentiation in tissue engineering. However, the study of the effect of clathrin-mediated …

[HTML][HTML] The influence of mannose-based esters on the mesophase behaviour of lyotropic liquid crystalline nanosystems as drug delivery vectors

M Tiboni, P Astolfi, M Verboni, S Benedetti… - Colloids and Surfaces B …, 2023 - Elsevier
Abstract Lyotropic Liquid Crystalline (LLC) nanoparticles represent an emerging class of
smart, biocompatible, and biodegradable systems for the delivery of drugs. Among these …

Melittin promotes dexamethasone in the treatment of adjuvant rheumatoid arthritis in rats

L Yang, X He, D Zhi, Y Xue, X Gong, K Dong… - Frontiers in …, 2024 - frontiersin.org
Background: Rheumatoid arthritis (RA) is an erosive-destructive inflammation of the joints,
and the chronic, long-term stiffness and deformation induced by RA are some of the …

[HTML][HTML] Traditional Chinese medicine Pien-Tze-Huang ameliorates LPS-induced sepsis through bile acid-mediated activation of TGR5-STAT3-A20 signalling

B Li, Y Zhang, X Liu, Z Zhang, S Zhuang… - Journal of …, 2024 - Elsevier
Abstract Pien Tze Huang (PZH), a class I nationally protected traditional Chinese medicine
(TCM), has been used to treat liver diseases such as hepatitis; however, the effect of PZH on …

[HTML][HTML] Osteogenic differentiation of encapsulated cells in dexamethasone-loaded phospholipid-induced silk fibroin hydrogels

C Laomeephol, H Ferreira, S Kanokpanont… - Biomaterials …, 2022 - ncbi.nlm.nih.gov
The tissue engineering triad comprises the combination of cells, scaffolds and biological
factors. Therefore, we prepared cell-and drug-loaded hydrogels using in situ silk fibroin (SF) …

Dexamethasone upregulates macrophage PIEZO1 via SGK1, suppressing inflammation and increasing ROS and apoptosis

H Liu, L Zhou, X Wang, Q Zheng, F Zhan, L Zhou… - Biochemical …, 2024 - Elsevier
The side effects of high-dose dexamethasone in anti-infection include increased ROS
production and immune cell apoptosis. Dexamethasone effectively activates …

A Novel Instantaneous Self-Assembled Hollow MOF-Derived Nanodrug for Microwave Thermo-Chemotherapy in Triple-Negative Breast Cancer

Q Wu, T Li, J Song, X Sun, X Ren, C Fu… - … Applied Materials & …, 2022 - ACS Publications
Hollow materials derived from metal–organic frameworks (MOFs) have emerged in the
biomedical field due to their unique properties, and different synthesis methods have been …