Thyroid dysfunction and diabetes mellitus are closely linked. Several studies have
documented the increased prevalence of thyroid disorders in patients with diabetes mellitus …

Immune checkpoints are small molecules expressed by immune cells that play critical roles
in maintaining immune homeostasis. Targeting the immune checkpoints cytotoxic T …

The most common cause of acquired thyroid dysfunction is autoimmune thyroid disease,
which is an organ-specific autoimmune disease with two presentation phenotypes …

Recent genetic studies have revealed shared immunological mechanisms in several
immune-related disorders that further our understanding of the development and …

Graves' disease is the most frequent cause of hyperthyroidism. Many questions remain
about the choice of diagnostic evaluations and treatment strategy according to clinical …

Hashimoto's thyroiditis (HT) is the most prevalent autoimmune thyroid disorder. Intrathyroidal
lymphocytic infiltration is followed by a gradual destruction of the thyroid gland which may …

Individuals with human immunodeficiency virus infection who commence antiretroviral
therapy when they are very immunodeficient are susceptible to immune reconstitution …

The polyglandular autoimmune syndromes (PAS) comprise a wide spectrum of autoimmune
disorders and are divided into a very rare juvenile (PAS type I) and a relatively common …

Studies using genome-wide platforms have yielded an unprecedented number of promising
signals of association between genomic variants and human traits. This Review addresses …

Background The risk factors for immune-related adverse events (irAEs) remain undefined.
Recently, a correlation between irAEs and clinical benefit was suggested. We examined the …