A brief review on DNA storage, compression, and digitalization

Y Cevallos, T Nakano, L Tello-Oquendo… - Nano Communication …, 2022 - Elsevier
Deoxyribonucleic acid (DNA) comprises four nucleotides and twenty amino acids (a
combination of nucleotides) that generate living organisms' structures. These discrete …

Domain-specific programming languages for computational nucleic acid systems

MR Lakin, A Phillips - ACS Synthetic Biology, 2020 - ACS Publications
The construction of models of system behavior is of great importance throughout science
and engineering. In bioengineering and bionanotechnology, these often take the form of …

BioCRNpyler: Compiling chemical reaction networks from biomolecular parts in diverse contexts

W Poole, A Pandey, A Shur, ZA Tuza… - PLOS Computational …, 2022 - journals.plos.org
Biochemical interactions in systems and synthetic biology are often modeled with chemical
reaction networks (CRNs). CRNs provide a principled modeling environment capable of …

Reservoir computing using DNA oscillators

X Liu, KK Parhi - ACS Synthetic Biology, 2022 - ACS Publications
This paper presents novel implementations for reservoir computing (RC) using DNA
oscillators. An RC system consists of two parts: reservoir and readout layer. The reservoir …

Supervised learning in a multilayer, nonlinear chemical neural network

D Arredondo, MR Lakin - IEEE Transactions on Neural …, 2022 - ieeexplore.ieee.org
The development of programmable or trainable molecular circuits is an important goal in the
field of molecular programming. Multilayer, nonlinear, artificial neural networks are a …

A cooperative DNA catalyst

DN Taylor, SR Davidson, L Qian - Journal of the American …, 2021 - ACS Publications
DNA catalysts are fundamental building blocks for diverse molecular information-processing
circuits. Allosteric control of DNA catalysts has been developed to activate desired catalytic …

Design and simulation of a multilayer chemical neural network that learns via backpropagation

MR Lakin - Artificial Life, 2023 - direct.mit.edu
The design and implementation of adaptive chemical reaction networks, capable of
adjusting their behavior over time in response to experience, is a key goal for the fields of …

Deep molecular programming: a natural implementation of binary-weight ReLU neural networks

M Vasic, C Chalk, S Khurshid… - … on Machine Learning, 2020 - proceedings.mlr.press
Embedding computation in molecular contexts incompatible with traditional electronics is
expected to have wide ranging impact in synthetic biology, medicine, nanofabrication and …

Algebraic biochemistry: a framework for analog online computation in cells

M Hemery, F Fages - … Conference on Computational Methods in Systems …, 2022 - Springer
The Turing completeness of continuous chemical reaction networks (CRNs) states that any
computable real function can be computed by a continuous CRN on a finite set of molecular …

Computing threshold circuits with void reactions in step chemical reaction networks

R Anderson, A Avila, B Fu, T Gomez, E Grizzell… - arXiv preprint arXiv …, 2024 - arxiv.org
We introduce a new model of\emph {step} Chemical Reaction Networks (step CRNs),
motivated by the step-wise addition of materials in standard lab procedures. Step CRNs …