Skin is the primary interface between the body and the environment. The spectrum of insults
to which skin is susceptible includes disorders caused by chemical and microbial agents …

Background Tacrolimus has been shown to be a powerful suppressor of the immune system.
It was introduced into clinical use to prevent allograft rejection and is now routinely used in …

Diagnose oral diseases quickly and accurately! Oral Pathology: Clinical Pathologic
Correlations, 7th Edition presents diseases and conditions by appearance and presentation …

Background: It is currently fashionable to consider atopic dermatitis (AD), like other
inflammatory dermatoses, as immunologic in pathogenesis (“inside-outside” hypothesis) …

Histidine decarboxylase (HDC) synthesizes histamine from histidine in mammals. To
evaluate the role of histamine, we generated HDC‐deficient mice using a gene targeting …

Atopic dermatitis is an inflammatory skin disease in which the inflammation is characterized
by the influx of lymphocytes into the dermis. It is generally believed that atopic dermatitis is a …

We have examined the expression of chemokines and their receptors in the atopic dermatitis–
like (AD-like) lesions of NC/Nga mice. Such lesions develop when the mice are kept in …

Background: Sera of patients with atopic dermatitis (AD) were found to have autoantibodies
that reacted with tissue culture cell substrates in immunohistochemistry to display a …

Background: We previously found that persimmon leaf extract contains antiallergic
substances that inhibit histamine release by human basophilic cell line KU812 in response …

In the present study, we examined the cytokine pattern expressed in situ during the
development of eczematous reactions that had been provoked in atopic dermatitis patients …