The cell biology of caveolae is a rapidly growing area of biomedical research. Caveolae are
known primarily for their ability to transport molecules across endothelial cells, but modern …

▪ Abstract Lipid raft microdomains were conceived as part of a mechanism for the
intracellular trafficking of lipids and lipid-anchored proteins. The raft hypothesis is based on …

Now available in a thoroughly revised Twelfth Edition, Wintrobe's Clinical Hematology
continues to be an industry leader with its ability to correlate basic science with the clinical …

One key tenet of the raft hypothesis is that the formation of glycosphingolipid-and cholesterol-
rich lipid domains can be driven solely by characteristic lipid-lipid interactions, suggesting …

Biochemical and cell-biological experiments have identified cholesterol as an important
component of lipid 'rafts' and related structures (eg, caveolae) in mammalian cell …

ABSTRACT A number of recent studies have demonstrated the significance of detergent-
insoluble, glycolipid-enriched membrane domains or lipid rafts, especially in regard to …

STRUCTURE OF PROTEIN GPI ANCHORS Although some of the plasma membrane
proteins of the parasitic protozoa use transmembrane polypeptide anchors, most of the …

Lipid rafts are membrane microdomains that are enriched in cholesterol and
glycosphingolipids. They have been implicated in processes as diverse as signal …

Detergent-insoluble membrane fragments that are rich in sphingolipid and cholesterol can
be isolated from both cell lysates and model membranes. We have proposed that these …

The discovery of glycosylphosphatidylinositol (GPI) membrane anchors has had a significant
impact on several areas of eukaryote cell biology. Studies of the African trypanosome, which …