[HTML][HTML] The emerging science of microdosing: A systematic review of research on low dose psychedelics (1955–2021) and recommendations for the field

V Polito, P Liknaitzky - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
The use of low doses of psychedelic substances (microdosing) is attracting increasing
interest. This systematic review summarises all empirical microdosing research to date …

Ethical and practical considerations for the use of psychedelics in psychiatry

GS Barber, CC Dike - Psychiatric Services, 2023 - Am Psychiatric Assoc
In recent years, psychedelic-assisted psychotherapies have reentered the realm of rigorous
scientific inquiry, garnering much attention from both the psychiatric community and the …

A Short Synthesis of Ergot Alkaloids and Evaluation of the 5-HT1/2 Receptor Selectivity of Lysergols and Isolysergols

NR Tasker, P Wipf - Organic letters, 2022 - ACS Publications
Key transformations in a four-step synthesis of the ergot alkaloid scaffold include a novel
cesium carbonate-mediated hydrogen autotransfer alkylation to generate the C (3)–C (4) …

LSD increases sleep duration the night after microdosing

N Allen, A Jeremiah, R Murphy, R Sumner… - Translational …, 2024 - nature.com
Microdosing psychedelic drugs at a level below the threshold to induce hallucinations is an
increasingly common lifestyle practice. However, the effects of microdosing on sleep have …

[HTML][HTML] Therapeutic role of psilocybin and 3, 4-methylenedioxymethamphetamine in trauma: A literature review

LN Fonseka, BK Woo - World Journal of Psychiatry, 2023 - ncbi.nlm.nih.gov
Abstract With the Food and Drug Administration designation in 2017 of 3, 4-
methylenedioxymethamphetamine (MDMA) as a breakthrough therapy in post-traumatic …

Psychedelics and schizophrenia: a double-edged sword

J Sapienza, F Martini, S Comai, R Cavallaro… - Molecular …, 2024 - nature.com
Psychedelics have shown promising effects in several psychiatric diseases as demonstrated
by multiple clinical trials. However, no clinical experiments on patients with schizophrenia …

PAM trial protocol: a randomised feasibility study of psychedelic microdosing–assisted meaning-centred psychotherapy in advanced stage cancer patients

A Wells, APS Muthukumaraswamy, E Morunga… - Pilot and Feasibility …, 2024 - Springer
Background An advanced cancer diagnosis can be associated with a significant profile of
distress. Psychedelic compounds have shown clinically significant effects in the treatment of …

Modulation of long-term potentiation following microdoses of LSD captured by thalamo-cortical modelling in a randomised, controlled trial

RJ Murphy, K Godfrey, AD Shaw… - BMC neuroscience, 2024 - Springer
Background Microdosing psychedelics is a phenomenon with claimed cognitive benefits that
are relatively untested clinically. Pre-clinically, psychedelics have demonstrated enhancing …

Multimodal creativity assessments following acute and sustained microdosing of lysergic acid diethylamide

RJ Murphy, RL Sumner, K Godfrey, A Mabidikama… - …, 2024 - Springer
Introduction Enhanced creativity is often cited as an effect of microdosing (taking repeated
low doses of a psychedelic drug). There have been recent efforts to validate the reported …

Less is more? A review of psilocybin microdosing

IA Savides, K Outhoff - Journal of Psychopharmacology, 2024 - journals.sagepub.com
Background: The applications of psilocybin, derived from 'magic mushrooms,'are vast,
including a burgeoning practice known as microdosing, which refers to the administration of …