Antibacterial compounds that reduce extracellular polymeric substances (EPS) are needed
to avoid bacterial biofilms in water pipelines. Herein, green one-pot synthesis of α …

Abstract Thieno [2, 3-d] pyrimidine fragment is not only bioistostere to quinazoline ring but
also to purines which exist in nucleic acids responsible for several key biological processes …

This work describes the design and synthesis of new hybrids of thienopyrimidine and
sulfonamides. The binding affinity of the prepared compounds to FGFR-1 enzyme and …

The study evaluated the antitumor efficacy of APAN,“synthesized indoloquinoline analog
derived from the parent neocryptolepine isolated from the roots of Cryptolepis …

The pyrimidine nucleus is a fundamental component of human DNA and RNA, as well as the
backbone of many therapeutic agents. Its significance in medicinal chemistry is well …

The current study evaluated the cytotoxic activity of 11-(1, 4-bisaminopropylpiperazinyl) 5-
methyl-5H-indolo [2, 3-b] quinoline (BAPPN), a novel derivative of 5-methyl-5H-indolo [2, 3 …

This work describes the design and synthesis of three series of hybrids of thienopyrimidines
and sulfonamides. Dihydrofolate reductase enzyme was selected as a target for the in-silico …

This work describes the synthesis of quinoline-based N--heterocyclic arenes and their
biological evaluation as molluscicides against adult Biomophalaria alexandrina snails as …

The present study describes the isolation and structural elucidation of bioactive natural
products from the hydro ethanol extract of Dilenia indica L. barks (DIHEEB) and their …