The role of oxidative stress in NAFLD–NASH–HCC transition—focus on NADPH oxidases

D Gabbia, L Cannella, S De Martin - Biomedicines, 2021 - mdpi.com
A peculiar role for oxidative stress in non-alcoholic fatty liver disease (NAFLD) and its
transition to the inflammatory complication non-alcoholic steatohepatitis (NASH), as well as …

Ferroptosis and metabolic dysfunction‐associated fatty liver disease: Is there a link?

G Feng, CD Byrne, G Targher, F Wang… - Liver …, 2022 - Wiley Online Library
Non‐alcoholic fatty liver disease (NAFLD), recently re‐defined and re‐classified as
metabolic dysfunction‐associated fatty liver disease (MAFLD), has become increasingly …

The effects of vitamin B12 supplementation on metabolic profile of patients with non-alcoholic fatty liver disease: a randomized controlled trial

HR Talari, MR Molaqanbari, M Mokfi, M Taghizadeh… - Scientific Reports, 2022 - nature.com
The present study is the first effort to evaluate the effects of vitamin B12 supplementation on
the serum level of liver enzymes, homocysteine, grade of hepatic steatosis, and metabolic …

The intestinal barrier and its dysfunction in patients with metabolic diseases and non-alcoholic fatty liver disease

R Forlano, BH Mullish, LA Roberts, MR Thursz… - International journal of …, 2022 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) represents an increasing cause of liver disease
worldwide, mirroring the epidemics of obesity and metabolic syndrome. As there are still no …

Oxidized lipids: common immunogenic drivers of non-alcoholic fatty liver disease and atherosclerosis

C Hoebinger, D Rajcic, T Hendrikx - Frontiers in cardiovascular …, 2022 - frontiersin.org
The prevalence of non-alcoholic fatty liver disease (NAFLD), ranging from simple steatosis
to inflammatory steatohepatitis (NASH) and cirrhosis, continues to rise, making it one of the …

Exploring the changes of peroxisomal polarity in the liver of mice with nonalcoholic fatty liver disease

Y Zhou, C Wu, X Wang, P Li, N Fan, W Zhang… - Analytical …, 2021 - ACS Publications
Peroxisome proliferator-activated receptor alpha (PPAR-a) is a crucial nuclear transcription
regulator of lipid metabolism, which is closely associated with the initiation and development …

High meat consumption is prospectively associated with the risk of non-alcoholic fatty liver disease and presumed significant fibrosis

D Ivancovsky-Wajcman, N Fliss-Isakov, LS Grinshpan… - Nutrients, 2022 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) has been associated with meat consumption in
cross-sectional studies. However, only a few prospective studies have been conducted, and …

Theabrownin ameliorates liver inflammation, oxidative stress, and fibrosis in MCD diet-fed C57BL/6J mice

Q Zhen, Q Liang, H Wang, Y Zheng, Z Lu… - Frontiers in …, 2023 - frontiersin.org
Introduction Nonalcoholic steatohepatitis (NASH), also known as metabolic steatohepatitis,
is a clinical syndrome with pathological changes like alcoholic hepatitis but without a history …

The effect of bioactive aliment compounds and micronutrients on non-alcoholic fatty liver disease

C Munteanu, B Schwartz - Antioxidants, 2023 - mdpi.com
In the current review, we focused on identifying aliment compounds and micronutrients, as
well as addressed promising bioactive nutrients that may interfere with NAFLD advance and …

The interplay between nonalcoholic fatty liver disease and atherosclerotic cardiovascular disease

AC Finney, S Das, D Kumar, MP McKinney… - Frontiers in …, 2023 - frontiersin.org
Therapeutic approaches that lower circulating low-density lipoprotein (LDL)-cholesterol
significantly reduced the burden of cardiovascular disease over the last decades. However …