Neuroinflammation is considered a balanced inflammatory response important in the
intrinsic repair process after injury or infection. Under chronic states of disease, injury, or …

One of the key features of cancer is energy metabolic reprogramming which is tightly related
to cancer proliferation, invasion, metastasis, and chemotherapy resistance. NcRNAs are a …

Abstract Background In plants, RNase III Dicer-like proteins (DCLs) act as sensors of
dsRNAs and process them into short 21-to 24-nucleotide (nt)(s) RNAs. Plant DCL4 is …

Elucidating the intricate interactions between viral pathogens and host cellular machinery
during infection is paramount for understanding pathogenic mechanisms and identifying …

Ferroptosis, a therapeutic strategy for tumours, is a regulated cell death characterised by the
increased accumulation of iron-dependent lipid peroxides (LPO). Tumour-associated long …

Background The tumor immune microenvironment (TIME) is an important regulator of tumor
progression, growth and metastasis. In addition, tumor metastasis is one of the principal …

Triple-negative breast cancer (TNBC) is among the most aggressive subtypes of the disease
that does not express estrogen receptor, progesterone receptor, and human epidermal …

由TP53 编码的P53 蛋白是防止细胞癌变所需的关键因子, 有广泛而强大的功能. P53
在诱导细胞周期停滞, DNA 损伤修复, 细胞凋亡和衰老等过程中发挥重要作用 …

Many types of gynecological cancer (GC) are often silent until they reach an advanced
stage, and are therefore often diagnosed too late for effective treatment. Hence, there is a …

P53 is a key factor encoded by the TP53, and it prevents cells from becoming cancerous and
has a wide range of powerful functions. p53 is found to play an important role in inducing …