We review studies from our laboratories using different molecular tools to characterize the
Amerindian, European and African ancestry of Brazilians. Initially we used uniparental DNA …

The genetic variation of our species reflects human demographic history and adaptation to
diverse local environments. Part of this genetic variation affects individual responses to …

Current Genome-Wide Association Studies (GWAS) rely on genotype imputation to increase
statistical power, improve fine-mapping of association signals, and facilitate meta-analyses …

We present the distribution of CYP 2D6, CYP 2C9, and CYP 2C19 variants and predicted
phenotypes in 33 native and admixed populations from Ibero‐America (n> 6,000) in the …

Focusing on literature published in 2018–2020, we review inferences about:(i) how ancient
DNA is contributing to clarify the peopling of the Americas and the dispersal of its first …

Abstract Purpose of Review Breast cancer incidence and mortality rates are lower in some
Hispanic/Latino subpopulations compared with non-Hispanic White women. However …

In adulthood, the ability to digest lactose, the main sugar present in milk of mammals, is a
phenotype (lactase persistence) observed in historically herder populations, mainly …

Genome-wide association studies (GWAS) have allowed the identification of disease-
associated variants, which can be leveraged to build polygenic scores (PGSs). Even though …

Genetic ancestry may contribute to ethnic differences in the risk of metabolic disorders.
Aging leads to a worse ability for homeostasis maintenance, favoring the establishment of …

Relationship between genetic ancestry and metabolic syndrome in community-dwelling old
adults Jamille Silva Oliveira a, b, c, Gabriel Novaes Miranda a, Icaro JS Ribeiro a, b, d, Ivna …