Abstract The Global Burden of Disease Study (GBD) began 30 years ago with the goal of
providing timely, valid and relevant assessments of critical health outcomes. Over this …

Infectious diseases and human behavior are intertwined. On one side, our movements and
interactions are the engines of transmission. On the other, the unfolding of viruses might …

Background Before 2020, mental disorders were leading causes of the global health-related
burden, with depressive and anxiety disorders being leading contributors to this burden. The …

Without modern medical management and vaccines, the severity of the Coronavirus
Disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome (SARS) …

We use COVID-19 case and mortality data from 1 February 2020 to 21 September 2020 and
a deterministic SEIR (susceptible, exposed, infectious and recovered) compartmental …

Background The COVID-19 pandemic and efforts to reduce SARS-CoV-2 transmission
substantially affected health services worldwide. To better understand the impact of the …

Background The infection-fatality ratio (IFR) is a metric that quantifies the likelihood of an
individual dying once infected with a pathogen. Understanding the determinants of IFR …

The COVID-19 pandemic has created an urgent need for models that can project epidemic
trends, explore intervention scenarios, and estimate resource needs. Here we describe the …

INTRODUCTION After initial declines, in mid-2020, a sustained resurgence in the
transmission of novel coronavirus disease (COVID-19) occurred in the United States …

Introduction The infection fatality rate (IFR) of COVID-19 has been carefully measured and
analysed in high-income countries, whereas there has been no systematic analysis of age …