The Drosophila imd signaling pathway

H Myllymäki, S Valanne, M Rämet - The Journal of Immunology, 2014 - journals.aai.org
The fruit fly, Drosophila melanogaster, has helped us to understand how innate immunity is
activated. In addition to the Toll receptor and the Toll signaling pathway, the Drosophila …

Tick vaccines: current status and future directions

J de la Fuente, M Contreras - Expert review of vaccines, 2015 - Taylor & Francis
Ticks and tick-borne diseases are a growing problem affecting human and animal health
worldwide. Traditional control methods, based primarily on chemical acaricides, have …

Tick galactosyltransferases are involved in α-Gal synthesis and play a role during Anaplasma phagocytophilum infection and Ixodes scapularis tick vector …

A Cabezas-Cruz, PJ Espinosa, P Alberdi, L Šimo… - Scientific reports, 2018 - nature.com
Abstract The carbohydrate Galα1-3Galβ1-(3) 4GlcNAc-R (α-Gal) is produced in all mammals
except for humans, apes and old world monkeys that lost the ability to synthetize this …

Rhipicephalus microplus: An overview of vaccine antigens against the cattle tick

DFS Pereira, HS Ribeiro, AAM Gonçalves… - Ticks and tick-borne …, 2022 - Elsevier
Rhipicephalus microplus, popularly known as the cattle tick, is the most important tick of
livestock as it is responsible for significant economic losses. The use of chemical acaricides …

Vaccinomics: A future avenue for vaccine development against emerging pathogens

J de la Fuente, M Contreras - Expert Review of Vaccines, 2021 - Taylor & Francis
Introduction Vaccines are a major achievement in medical sciences, but the development of
more effective vaccines against infectious diseases is essential for prevention and control of …

Tick vaccines and the control of tick-borne pathogens

O Merino, P Alberdi, JM Pérez de la Lastra… - Frontiers in cellular …, 2013 - frontiersin.org
Ticks are obligate hematophagous ectoparasites that transmit a wide variety of pathogens to
humans and animals. The incidence of tick-borne diseases has increased worldwide in both …

Metazoan parasite vaccines: present status and future prospects

C Stutzer, SA Richards, M Ferreira, S Baron… - Frontiers in cellular …, 2018 - frontiersin.org
Eukaryotic parasites and pathogens continue to cause some of the most detrimental and
difficult to treat diseases (or disease states) in both humans and animals, while also …

Vaccination with proteins involved in tick–pathogen interactions reduces vector infestations and pathogen infection

O Merino, S Antunes, J Mosqueda, JA Moreno-Cid… - Vaccine, 2013 - Elsevier
Tick-borne pathogens cause diseases that greatly impact animal health and production
worldwide. The ultimate goal of tick vaccines is to protect against tick-borne diseases …

Quantum vaccinomics platforms to advance in vaccinology

J de la Fuente, M Contreras - Frontiers in Immunology, 2023 - frontiersin.org
The opinion flows from Introduction to the immunological quantum that requires a historical
perspective, to Quantum vaccine algorithms supported by a bibliometric analysis, to …

Functional evolution of subolesin/akirin

S Artigas-Jerónimo, M Villar, A Cabezas-Cruz… - Frontiers in …, 2018 - frontiersin.org
The Subolesin/Akirin constitutes a good model for the study of functional evolution because
these proteins have been conserved throughout the metazoan and play a role in the …