Cyclooxygenases-2 (COX-2) and Prostaglandin E2 (PGE2), which are important in chronic
inflammatory diseases, can increase tumor incidence and promote tumor growth and …

The cytoplasmic events that control mammalian gene expression, primarily mRNA stability
and translation, potently influence the cellular response to internal and external signals. The …

The human embryonic lethal abnormal vision-like protein, HuR, is a member of the Hu family
of RNA-binding proteins. Over the past decade, this ubiquitously expressed protein has …

Cancer‐related gene expression programs are strongly influenced by posttranscriptional
mechanisms. The RNA‐binding protein HuR is highly abundant in many cancers. Numerous …

Abstract Background Circular RNAs (circRNAs), a subclass of non-coding RNAs, play
essential roles in tumorigenesis and aggressiveness. Our previous study has identified that …

Background Despite the success of modern chemotherapy in the treatment of large bowel
cancers, patients with metastatic gastric cancer continue to have a dismal outcome …

Medulloblastomas are the most common malignant brain tumors in children. They express
high levels of COX-2 and produce PGE2, which stimulates tumor cell proliferation. Human …

The immensity of genes and molecules implicated in gastric carcinogenesis is
overwhelming and the relevant importance of some of these molecules is too often unclear …

MicroRNAs (miRNAs) are a class of naturally occurring, small, non-coding RNAs that control
gene expression during development, normal cell function, and disease. Although there is …

BACKGROUND & AIMS: During tumorigenesis, loss of rapid messenger RNA (mRNA)
decay allows for overexpression of cancer-associated genes. The RNA-binding proteins Hu …