Breast cancer is one of the most important causes of cancer related morbidity and mortality
in the world. Along with genetic, environmental factors also play a multifaceted role in the …

Pancreatic cancer is a malignancy arising from the endocrine or exocrine compartment of
this organ. Tumors from exocrine origin comprise over 90% of all pancreatic cancers …

Prostate cancer is the third most commonly diagnosed cancer among Pakistani men. It is a
multifactorial disease involving genetics together with environmental factors. Countries …

Genetic polymorphisms constitute one of the reasons behind the racial variation in prostate
cancer occurrence. Published studies regarding genetic associations of glutathione S …

Abstract Glutathione-S-transferases (GSTs) not only show cytoprotective role and their
involvement in the development of anticancer drug resistance, but also transmit signals that …

Abstract Histone lysine methyltransferase 2 (KMT2) proteins form multimeric enzymatic
complexes that methylate lysine 4 on histone H3 (H3K4) at transcription regulatory elements …

XPG polymorphisms are associated with varied clinical outcomes in different cancers but up-
till now no study has been reported on breast cancer. Therefore, current study was aimed to …

Therapeutic proteins are utilized in a variety of clinical applications, but side effects and
rapid in vivo clearance still present hurdles. An approach that addresses both drawbacks is …

ERCC5 plays crucial role in excision repair DNA damage induced by UV in NER pathway.
Single neuleotide polymorphism in ERCC5 were responsible for different cancers …

Aim: To analyze the mutations of KRAS and BRAF in LC patients among Pakistani
population. Settings and Design: The study has been carried out at universities and health …