Abstract Treatment resistant schizophrenia (TRS) refers to the significant proportion of
schizophrenia patients who continue to have symptoms and poor outcomes despite …

This review will discuss the role of childhood trauma in bipolar disorders. Relevant studies
were identified via Medline (PubMed) and PsycINFO databases published up to and …

Traumatic life events have been robustly associated with various psychosis outcomes,
including increased risk of psychotic disorders, the prodrome of psychosis, and dimensional …

There is a growing body of research focused on the relationship between childhood trauma
and the risk of developing psychosis. Numerous studies, including many large-scale …

Objective: Pharmacogenomic studies of antipsychotics have typically examined effects of
individual polymorphisms. By contrast, polygenic risk scores (PRSs) derived from genome …

In recent years, empirical data and theoretical accounts relating to the relationship between
childhood victimization and psychotic experiences have accumulated. Much of this work has …

Up to 30% of people with schizophrenia do not respond to two (or more) trials of
dopaminergic antipsychotics. They are said to have treatment-resistant schizophrenia (TRS) …

Around 30% of patients with schizophrenia show an inadequate response to antipsychotics—
ie, treatment resistance. Neuroimaging studies can help to uncover the underlying …

Auditory verbal hallucinations (AVH:'hearing voices') are found in both schizophrenia and
post-traumatic stress disorder (PTSD). In this paper we first demonstrate that AVH in these …

Background It has been proposed that repetitive negative thinking (worry and rumination)
may be more common among adults who have been exposed to childhood adverse …