While microelectrode arrays (MEAs) offer the promise of elucidating functional neural
circuitry and serve as the basis for a cortical neuroprosthesis, the challenge of designing …

The human brain, with its vast network of billions of neurons and trillions of synapses
(connections) between diverse cell types, remains one of the greatest mysteries in science …

Neural population dynamics relevant to behavior vary over multiple spatial and temporal
scales across three-dimensional volumes. Current optical approaches lack the spatial …

Objective. Optical fiber devices constitute significant tools for the modulation and
interrogation of neuronal circuitry in the mid and deep brain regions. The illuminated brain …

In implantable electrophysiological recording systems, the headstage typically comprises
neural probes that interface with brain tissue and integrated circuit chips for signal …

The field of implantable optical neural interfaces has recently enabled the interrogation of
neural circuitry with both cell-type specificity and spatial resolution in sub-cortical structures …

Abstract Calcium (Ca 2+) fluorescence is widely used to monitor the activity of neurons in
vivo. We propose a method of detection the Ca 2+ fluorescence intensity by integrating a …

Striatal acetylcholine (ACh) has been linked to behavioral flexibility. A key component of
flexibility is down-regulating responding as valued cues and actions become decoupled …

Fiber photometry is an emerging technique enabling the monitoring of neural activity in vivo
by employing optical fibers to detect functional fluorescence variations from specific …

The objective of this paper is to fabricate a flexible mid-infrared (IR) light delivery system with
bioprobesince remarkable biological effect of mid-IR light and lack of corresponding …