Tissue engineering and regenerative medicine involve many different artificial and biologic
materials, frequently integrated in composite scaffolds, which can be repopulated with …

Seriously compromised function of some organs can only be restored by transplantation.
Due to the shortage of human donors, the need to find another source of organs is of primary …

Liver transplantation is currently the only effective treatment for patients with end-stage liver
disease; however, donor liver scarcity is a notable concern. As a result, extensive endeavors …

Last twenties, tissue engineering has rapidly advanced to address the shortage of organ
donors. Decellularization techniques have been developed to mitigate immune rejection …

Heart failure is a progressive deterioration of cardiac pump function over time and is often a
manifestation of ischemic injury caused by myocardial infarction (MI). Post-MI, structural …

Background: Cardiovascular surgery is confronted by a lack of suitable materials for patch
repair. Acellular animal tissues serve as an abundant source of promising biomaterials. The …

In terms of large bone defect reconstructions, massive bone allografts may sometimes be the
only solution. However, they are still burdened with a high postoperative complication rate …

Introduction Large bone defects are challenging for surgeons. Available reimplanted bone
substitutes can't properly restore optimal function along and long term osteointegration of the …

Regenerative medicine and tissue engineering are reasonable techniques for repairing
failed tissues and could be a suitable alternative to organ transplantation. One of the most …

The lack of viability of massive bone allografts for critical-size bone defect treatment remains
a challenge in orthopedic surgery. The literature has reviewed the advantages of a multi …