This chapter outlines some general issues in searching for studies; describes the main
sources of potential studies; and discusses how to plan the search process, design and …

Background Systematic reviews may be compromised by selective inclusion and reporting
of outcomes and analyses. Selective inclusion occurs when there are multiple effect …

Background: Industry funding and financial conflicts of interest may contribute to bias in the
synthesis and interpretation of scientific evidence. Objective: To examine the association …

Background Research indicates that the methods used to identify data for systematic
reviews of adverse effects may need to differ from other systematic reviews. Objectives To …

Systematic reviews aim to summarize all evidence using very rigorous methods in order to
address a specific research question with less bias as possible. Systematic reviews are …

Although qualitative researches (QR) are invaluable in understanding complex healthcare
situations, the quantitative systematic reviews could not treat them. To improve quality of …

This article overviews evidence on common instances of conflict of interest (COI) in research
publications from general and specialized fields of biomedicine. Financial COIs are viewed …

Anti-TNF agents and other biologic therapies are widely prescribed for a variety of
indications, with total sales that exceed $200 billion to date. In rheumatic diseases, biologic …

Introduction As standardized reporting requirements for systematic reviews are being
adopted more widely, review authors are under greater pressure to accurately record their …

Background Treatment and diagnostic recommendations are often made in clinical
guidelines, reports from advisory committee meetings, opinion pieces such as editorials, and …