Advancements and challenges in stem cell transplantation for regenerative medicine

L Wei, W Yan, W Shah, Z Zhang, M Wang, B Liu, Z Xue… - Heliyon, 2024 - cell.com
Stem cell transplantation has emerged as a promising avenue in regenerative medicine,
potentially facilitating tissue repair in degenerative diseases and injuries. This review …

Emerging biomarkers for precision diagnosis and personalized treatment of cystic fibrosis

TA Addissouky, IETE Sayed, MMA Ali, Y Wang - Journal of Rare Diseases, 2024 - Springer
Background Cystic fibrosis (CF) is a fatal genetic disorder caused by mutations in the cystic
fibrosis transmembrane conductance regulator (CFTR) gene, disrupting ion transport. This …

ERS international Congress 2023: highlights from the Basic and Translational Sciences Assembly

KD Reddy, N Bizymi, A Schweikert… - ERJ Open …, 2024 - Eur Respiratory Soc
Early career members of Assembly 3 (Basic and Translational Sciences) of the European
Respiratory Society (ERS) summarise the key messages discussed during six selected …

Unlocking the potential of CRISPR-Cas9 for cystic fibrosis: A detailed review

H Harris, J Kittur - Gene, 2025 - Elsevier
CRISPR-Cas9 technology has revolutionized genetic engineering, offering precise and
efficient genome editing capabilities. This review explores the application of CRISPR-Cas9 …

Early career member highlights from the 22nd ERS Lung Science Conference: development of chronic lung diseases–from life-spanning mechanisms to preventive …

CY Wu, MC Melo-Narváez… - ERJ Open …, 2024 - publications.ersnet.org
Extract The 22nd Lung Science Conference (LSC) organised by the European Respiratory
Society (ERS) took place on the 14–17 March 2024 online and in person in Estoril, Portugal …

Редактирование мутации c. 3846G> A (p. Trp1282*) в гене CFTR в ИПСК с использованием аденинового редактора

ЕВ Кондратьева, АГ Демченко… - Медицинская …, 2023 - medgen-journal.ru
Аннотация Муковисцидоз (МВ)–аутосомно-рецессивное заболевание, обусловленное
мутациями в гене CFTR, приводящими к дисбалансу ионов хлора и натрия в …

Обзор текущих исследований по разработке генной терапии на основе геномного редактирования для лечения муковисцидоза

СА Смирнихина - Медицинская генетика, 2024 - medgen-journal.ru
Аннотация Муковисцидоз (МВ)–частое моногенное заболевание, возникающее в
результате мутаций в гене CFTR. Патогенетическая терапия, несмотря на ее высокую …

Lung Science Conference highlights 2023: Post-viral lung diseases–from basic immunology to clinical phenotypes and therapy

SC Ocaña, C DeSanti, K Daly, C Shrees, N László… - Breathe, 2023 - Eur Respiratory Soc
Lung Science Conference highlights 2023: Post-viral lung diseases – from basic immunology
to clinical phenotypes and therapy | European Respiratory Society Skip to main content Main …

In vitro modelling of respiratory infections in idiopathic pulmonary fibrosis (IPF) using human induced pluripotent stem cell (hiPSCs)-derived alveolar epithelial type II …

AL Serna Valverde - eprints.nottingham.ac.uk
Idiopathic pulmonary fibrosis (IPF) is a chronic, interstitial lung disease estimated to affect
4.5 individuals per 10,000 [1]. It is characterised by the accumulation of extracellular matrix …

[PDF][PDF] Generation of hiPSC-Derived Intestinal Organoids for Developmental and Disease Modelling Applications

PM Durczak, KL Fair, N Jinks… - Journal of …, 2024 - nottingham-repository.worktribe.com
The resulting organoids can be used to model human intestinal development as well as
numerous human intestinal diseases including inflammatory bowel disease. To model …