Phagosome maturation is the process by which internalized particles (such as bacteria and
apoptotic cells) are trafficked into a series of increasingly acidified membrane-bound …

Phagocytosis requires receptor-mediated recognition of particles, usually in the guise of
infectious agents and apoptotic cells. Phagosomes fuse with lysosomes to generate …

Giant viruses such as Mimivirus isolated from amoeba found in aquatic habitats show
biological sophistication comparable to that of simple cellular life forms and seem to evolve …

Phagosomes are fascinating subcellular structures. After all, there are only a few
compartments that are born before our very eyes and whose development we can follow in a …

The intestinal parasite Entamoeba histolytica is one of the first protists for which a draft
genome sequence has been published. Although the genome is still incomplete, it is …

Phagocytosis is an important component of innate and adaptive immunity. The formation of
phagosomes and the subsequent maturation that capacitates them for pathogen elimination …

From early on in evolution, organisms have had to protect themselves from pathogens.
Mechanisms for discriminating “self” from “non‐self” evolved to accomplish this task …

Vesicular trafficking plays an important role in a virulence mechanism of the enteric
protozoan parasite Entamoeba histolytica as secreted and lysosomal cysteine protease (CP) …

The mucosal microbiota is recognised as an important factor for our health, with many
disease states linked to imbalances in the normal community structure. Hence, there is …

Paucimannosidic proteins (PMPs) are bioactive glycoproteins carrying truncated α‐or β‐
mannosyl‐terminating asparagine (N)‐linked glycans widely reported across the eukaryotic …