Perspective on musculoskeletal modelling and predictive simulations of human movement to assess the neuromechanics of gait

F De Groote, A Falisse - Proceedings of the Royal …, 2021 - royalsocietypublishing.org
Locomotion results from complex interactions between the central nervous system and the
musculoskeletal system with its many degrees of freedom and muscles. Gaining insight into …

OpenCap: Human movement dynamics from smartphone videos

SD Uhlrich, A Falisse, Ł Kidziński… - PLoS computational …, 2023 - journals.plos.org
Measures of human movement dynamics can predict outcomes like injury risk or
musculoskeletal disease progression. However, these measures are rarely quantified in …

A review of the efforts to develop muscle and musculoskeletal models for biomechanics in the last 50 years

JM Wakeling, M Febrer-Nafría, F De Groote - Journal of biomechanics, 2023 - Elsevier
Both the Hill and the Huxley muscle models had already been described by the time the
International Society of Biomechanics was founded 50 years ago, but had seen little use …

Opensim moco: Musculoskeletal optimal control

CL Dembia, NA Bianco, A Falisse… - PLOS Computational …, 2020 - journals.plos.org
Musculoskeletal simulations are used in many different applications, ranging from the
design of wearable robots that interact with humans to the analysis of patients with impaired …

Predictive simulations of running gait reveal a critical dynamic role for the tail in bipedal dinosaur locomotion

PJ Bishop, A Falisse, F De Groote, JR Hutchinson - Science advances, 2021 - science.org
Locomotion has influenced the ecology, evolution, and extinction of species throughout
history, yet studying locomotion in the fossil record is challenging. Computational …

Physics-based simulations to predict the differential effects of motor control and musculoskeletal deficits on gait dysfunction in cerebral palsy: a retrospective case …

A Falisse, L Pitto, H Kainz, H Hoang… - Frontiers in human …, 2020 - frontiersin.org
Physics-based simulations of walking have the theoretical potential to support clinical
decision-making by predicting the functional outcome of treatments in terms of walking …

Sensor-based computational approach to preventing back injuries in construction workers

S Subedi, N Pradhananga - Automation in construction, 2021 - Elsevier
Repetitive labor-intensive tasks are common in civil construction projects. Construction
workers are prone to getting into musculoskeletal disorders-related injuries while performing …

Efficient trajectory optimization for curved running using a 3D musculoskeletal model with implicit dynamics

M Nitschke, E Dorschky, D Heinrich, H Schlarb… - Scientific reports, 2020 - nature.com
Trajectory optimization with musculoskeletal models can be used to reconstruct measured
movements and to predict changes in movements in response to environmental changes. It …

Modeling toes contributes to realistic stance knee mechanics in three-dimensional predictive simulations of walking

A Falisse, M Afschrift, F De Groote - PLoS One, 2022 - journals.plos.org
Physics-based predictive simulations have been shown to capture many salient features of
human walking. Yet they often fail to produce realistic stance knee and ankle mechanics …

Computational modelling of muscle fibre operating ranges in the hindlimb of a small ground bird (Eudromia elegans), with implications for modelling locomotion in …

PJ Bishop, KB Michel, A Falisse, AR Cuff… - PLoS Computational …, 2021 - journals.plos.org
The arrangement and physiology of muscle fibres can strongly influence musculoskeletal
function and whole-organismal performance. However, experimental investigation of muscle …