Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation

JAHR Claassen, DHJ Thijssen… - Physiological …, 2021 - journals.physiology.org
Brain function critically depends on a close matching between metabolic demands,
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …

Physiology of sedentary behavior

AJ Pinto, A Bergouignan, PC Dempsey… - Physiological …, 2023 - journals.physiology.org
Sedentary behaviors (SB) are characterized by low energy expenditure while in a sitting or
reclining posture. Evidence relevant to understanding the physiology of SB can be derived …

The effects of acute exposure to prolonged sitting, with and without interruption, on peripheral blood pressure among adults: a systematic review and meta-analysis

C Paterson, S Fryer, K Stone, G Zieff, L Turner, L Stoner - Sports Medicine, 2022 - Springer
Background Previous reviews have shown that exposure to acute prolonged sitting can
have detrimental effects on several cardiovascular and cardiometabolic health markers …

Effectiveness of an intervention to reduce sedentary behaviour as a personalised secondary prevention strategy for patients with coronary artery disease: main …

BMA Van Bakel, SH Kroesen, EA Bakker… - International Journal of …, 2023 - Springer
Background A high sedentary time is associated with increased mortality risk. Previous
studies indicate that replacement of sedentary time with light-and moderate-to-vigorous …

Detrimental effects of physical inactivity on peripheral and brain vasculature in humans: Insights into mechanisms, long-term health consequences and protective …

A Daniele, SJE Lucas, C Rendeiro - Frontiers in Physiology, 2022 - frontiersin.org
The growing prevalence of physical inactivity in the population highlights the urgent need for
a more comprehensive understanding of how sedentary behaviour affects health, the …

[HTML][HTML] Sedentary behaviour and brain health in middle-aged and older adults: A systematic review

CM Maasakkers, RWJ Weijs, C Dekkers… - Neuroscience & …, 2022 - Elsevier
Sedentary behaviour may increase the risk of dementia. Studying physiological effects of
sedentary behaviour on cerebral health may provide new insights into the nature of this …

A proposed hypothesis on dementia: inflammation, small vessel disease, and hypoperfusion is the sequence that links all harmful lifestyles to cognitive impairment

AM Hakim - Frontiers in Aging Neuroscience, 2021 - frontiersin.org
There is growing consensus that certain lifestyles can contribute to cognitive impairment and
dementia, but the physiological steps that link a harmful lifestyle to its negative impact are …

Effect of sedentary behavior interventions on vascular function in adults: A systematic review and meta‐analysis

C Zheng, X Zhang, S Sheridan, RST Ho… - … Journal of Medicine …, 2021 - Wiley Online Library
Sedentary behavior (SB) results in hemodynamic alterations within the vasculature, leading
to vascular dysfunction that may be attenuated by various interventions. This systematic …

The physiological benefits of sitting less and moving more: opportunities for future research

CL Hwang, SH Chen, CH Chou, G Grigoriadis… - Progress in …, 2022 - Elsevier
Sedentary behavior (SB) and physical activity (PA) are important risk factors of
cardiovascular disease morbidity and mortality. In addition to increasing the amount of …

The Physiological and Molecular Links Between Physical Activity and Brain Health: A Review

S Schock, A Hakim - Neuroscience Insights, 2023 - journals.sagepub.com
There is currently an epidemic of sedentary behavior throughout the world, leading to
negative impacts on physical health and contributing to both mortality and burden of …