Clostridioides difficile is a Gram-positive anaerobe that can cause a spectrum of disorders
that range in severity from mild diarrhoea to fulminant colitis and/or death. The bacterium …

Infection of the colon with the Gram-positive bacterium Clostridium difficile is potentially life
threatening, especially in elderly people and in patients who have dysbiosis of the gut …

Clostridium difficile is a bacterial pathogen that is the leading cause of nosocomial antibiotic-
associated diarrhea and pseudomembranous colitis worldwide. The incidence, severity …

Clostridioides difficile is the most common cause of nosocomial antibiotic-associated
diarrhea, and is responsible for a spectrum of diseases characterized by high levels of …

Binary toxin (CDT) is frequently observed in Clostridium difficile strains associated with
increased severity of C. difficile infection (CDI). CDT belongs to the family of binary ADP …

Clostridium difficile is now considered to be one of the most important causes of health care-
associated infections. C. difficile infections are also emerging in the community and in …

Clostridium difficile is the leading cause of infectious diarrhoea in hospitals worldwide,
because of its virulence, spore-forming ability and persistence,. C. difficile-associated …

Clostridium difficile is a leading cause of antibiotic-associated diarrhea, a significant animal
pathogen, and a worldwide public health burden. Most disease-causing strains secrete two …

Background The continued rise of Clostridium difficile infections worldwide has been
accompanied by the rapid emergence of a highly virulent clone designated PCR-ribotype …

Clostridium difficile causes antibiotic-associated diarrhea and pseudomembranous colitis by
production of the Rho GTPase-glucosylating toxins A and B. Recently emerging …