Recent developments in PET instrumentation

H Peng, C S. Levin - Current pharmaceutical biotechnology, 2010 - benthamdirect.com
Positron emission tomography (PET) is used in the clinic and in vivo small animal research
to study molecular processes associated with diseases such as cancer, heart disease, and …

Quantitative preclinical PET imaging: opportunities and challenges

C Kuntner, D Stout - Frontiers in physics, 2014 - frontiersin.org
PET imaging of metabolism involves many choices, from hardware settings, software options
to animal handling considerations. How to decide what settings or conditions to use is not …

NEMA NU 4-2008 comparison of preclinical PET imaging systems

AL Goertzen, Q Bao, M Bergeron… - Journal of nuclear …, 2012 - Soc Nuclear Med
The National Electrical Manufacturers Association (NEMA) standard NU 4-2008 for
performance measurements of small-animal tomographs was recently published. Before this …

On light sharing TOF-PET modules with depth of interaction and 157 ps FWHM coincidence time resolution

M Pizzichemi, A Polesel, G Stringhini… - Physics in Medicine …, 2019 - iopscience.iop.org
The performance of a light sharing and recirculation mechanism that allows the extraction of
depth of interaction (DOI) are investigated in this paper, with a particular focus on timing. In …

Monolithic scintillator PET detectors with intrinsic depth-of-interaction correction

MC Maas, DR Schaart, DJJ van der Laan… - Physics in Medicine …, 2009 - iopscience.iop.org
We developed positron emission tomography (PET) detectors based on monolithic
scintillation crystals and position-sensitive light sensors. Intrinsic depth-of-interaction (DOI) …

Optical simulation of monolithic scintillator detectors using GATE/GEANT4

DJ van der Laan, DR Schaart, MC Maas… - Physics in Medicine …, 2010 - iopscience.iop.org
Much research is being conducted on position-sensitive scintillation detectors for medical
imaging, particularly for emission tomography. Monte Carlo simulations play an essential …

The current state, challenges and perspectives of MR-PET

H Herzog, U Pietrzyk, NJ Shah, K Ziemons - Neuroimage, 2010 - Elsevier
Following the success of PET/CT during the last decade and the recent increasing
proliferation of SPECT/CT, another hybrid imaging instrument has been gaining more and …

New imaging technologies to enhance the molecular sensitivity of positron emission tomography

CS Levin - Proceedings of the IEEE, 2008 - ieeexplore.ieee.org
Positron emission tomography (PET) is used in the clinic and in vivo small animal research
to study certain molecular processes associated with diseases such as cancer, heart …

NEMA NU-4 performance evaluation of PETbox4, a high sensitivity dedicated PET preclinical tomograph

Z Gu, R Taschereau, NT Vu, H Wang… - Physics in Medicine …, 2013 - iopscience.iop.org
PETbox4 is a new, fully tomographic bench top PET scanner dedicated to high sensitivity
and high resolution imaging of mice. This manuscript characterizes the performance of the …

Current trends in preclinical PET system design

CS Levin, H Zaidi - PET clinics, 2007 - Elsevier
PET is used in laboratory small-animal research to visualize and track certain molecular
processes associated with diseases such as cancer, heart disease, and neurologic …