An Evaluation of Zebrafish, an Emerging Model Analyzing the Effects of Toxicants on Cognitive and Neuromuscular Function

T Clevenger, J Paz, A Stafford… - International Journal …, 2024 - journals.sagepub.com
An emerging alternative to conventional animal models in toxicology research is the
zebrafish. Their accelerated development, regenerative capacity, transparent physical …

Environmentally relevant concentrations of triclocarban affect behaviour, learning, and brain gene expression in fish

T Lucon-Xiccato, BB Savaşçı, C Merola… - Science of The Total …, 2023 - Elsevier
Many chemicals spilled in aquatic ecosystems can interfere with cognitive abilities and brain
functions that control fitness-related behaviour. Hence, their harmful potential may be …

Early developmental exposure to bisphenol A and bisphenol S disrupts socio-cognitive function, isotocin equilibrium, and excitation-inhibition balance in developing …

M Naderi, P Puar, R JavadiEsfahani, RWM Kwong - Neurotoxicology, 2022 - Elsevier
Dysregulation of the oxytocinergic system and excitation/inhibition (E/I) balance in synaptic
transmission and neural circuits are common hallmarks of various neurodevelopmental …

Embryonic ethanol exposure and optogenetic activation of hypocretin neurons stimulate similar behaviors early in life associated with later alcohol consumption

AD Collier, N Yasmin, O Karatayev, AR Abdulai… - Scientific Reports, 2024 - nature.com
The initiation of alcohol use early in life is one of the strongest predictors of developing a
future alcohol use disorder. Clinical studies have identified specific behaviors during early …

Baicalein 5, 6-dimethyl ether prevents memory deficits in the scopolamine zebrafish model by regulating cholinergic and antioxidant systems

I Brinza, IM Ayoub, OA Eldahshan, L Hritcu - Plants, 2021 - mdpi.com
Baicalein 5, 6-dimethyl ether, a bioactive flavonoid isolated for the first time from Alnus
rugosa, was explored for its capability to relieve memory deficits and decrease oxidative …

Environmental enrichment decreases anxiety‐like behavior in zebrafish larvae

E Gatto, M Dadda, M Bruzzone… - Developmental …, 2022 - Wiley Online Library
The development of anxiety disorders is often linked to individuals' negative experience. In
many animals, development of anxiety‐like behavior is modeled by manipulating …

Stimulus characteristics, learning bias and visual discrimination in zebrafish (Danio rerio)

M Santacà, M Dadda, MEM Petrazzini, A Bisazza - Behavioural Processes, 2021 - Elsevier
Zebrafish is an emerging model in the study of brain function; however, knowledge about its
behaviour and cognition is incomplete. Previous studies suggest this species has limited …

Innate visual discrimination abilities of zebrafish larvae

E Gatto, M Bruzzone, T Lucon-Xiccato - Behavioural processes, 2021 - Elsevier
The ability to discriminate between objects visually plays a key role in animals' interactions
with their environment because it enables them to recognise companions, prey, and …

Development of Open-Field Behaviour in the Medaka, Oryzias latipes

T Lucon-Xiccato, F Conti, F Loosli, NS Foulkes… - Biology, 2020 - mdpi.com
Simple Summary Animal models play an important role in research on behaviour and its
impairment. Fish larvae allow researchers to conduct experiments on large samples in just a …

Medaka as a model for seasonal plasticity: Photoperiod-mediated changes in behaviour, cognition, and hormones

T Lucon-Xiccato, G Montalbano, E Frigato, F Loosli… - Hormones and …, 2022 - Elsevier
Teleosts display the highest level of brain plasticity of all vertebrates. Yet we still know little
about how seasonality affects fish behaviour and the underlying cognitive mechanisms …