Thrombocytopenia and platelet transfusion in the neonate

M Cremer, H Sallmon, PJ Kling, C Bührer… - Seminars in Fetal and …, 2016 - Elsevier
Neonatal thrombocytopenia is widespread in preterm and term neonates admitted to
neonatal intensive care units, with up to one-third of infants demonstrating platelet counts< …

Thrombopoietin receptor agonist for treatment of immune thrombocytopenia in pregnancy: a narrative review

N Agarwal, A Mangla - Therapeutic advances in hematology, 2021 - journals.sagepub.com
The treatment of immune thrombocytopenia (ITP) in adults has evolved rapidly over the past
decade. The second-generation thrombopoietin receptor agonists (TPO-RAs), romiplostim …

Distinct differences in platelet production and function between neonates and adults: implications for platelet transfusion practice

F Ferrer‐Marin, S Stanworth, C Josephson… - …, 2013 - Wiley Online Library
Thrombocytopenia is a common problem among sick neonates admitted to the neonatal
intensive care unit. Among neonates, preterm infants are the subgroup at highest risk for …

Updates in neonatal hematology: causes, risk factors, and management of anemia and thrombocytopenia

IMC Ree, E Lopriore - Hematology/Oncology Clinics, 2019 - hemonc.theclinics.com
Anemia and thrombocytopenia are common hematologic disorders in neonates, particularly
in (very) preterm neonates. Blood products, either red blood cells (RBC) or platelets to …

Thrombocytopenia, bleeding, and use of platelet transfusions in sick neonates

SJ Stanworth - Hematology 2010, the American Society of …, 2012 - ashpublications.org
Survival rates for infants born prematurely have improved significantly, in part due to better
supportive care such as RBC transfusion. The role of platelet transfusions in neonates is …

Neonatal thrombocytopenia and platelet transfusion-a UK perspective

R Carr, AM Kelly, LM Williamson - Neonatology, 2014 - karger.com
Five percent of newborn infants admitted to UK neonatal units during a recent study
developed a platelet count< 60× 109/l, and 60% of these were transfused platelets. This …

Thrombocytopenia in small-for-gestational-age infants

RD Christensen, VL Baer, E Henry, GL Snow… - …, 2015 - publications.aap.org
BACKGROUND: Thrombocytopenia is common among small-for-gestational-age (SGA)
neonates (birth weight< 10th percentile reference range), but several aspects of this …

Thrombocytopenia in late preterm and term neonates after perinatal asphyxia

RD Christensen, VL Baer, HM Yaish - Transfusion, 2015 - Wiley Online Library
Background A recent NHLBI conference concluded that platelet (PLT) transfusions of
neonates must become more evidence based. One neonatal disorder for which transfusions …

Platelet transfusion in the neonatal intensive care unit: benefits, risks, alternatives

RD Christensen - Neonatology, 2011 - karger.com
Platelet transfusions were introduced into clinical medicine about 60 years ago when they
were shown to reduce the mortality rate of patients with leukemia who were bleeding …

Evaluation and management of thrombocytopenic neonates in the intensive care unit

A Del Vecchio - Early human development, 2014 - Elsevier
Thrombocytopenia is a very frequent problem among sick neonates, affecting up to 35% of
all infants admitted to the neonatal intensive care unit (NICU), and serves as an important …