Hand, foot, and mouth disease associated with coxsackievirus A10: more serious than it seems

L Bian, F Gao, Q Mao, S Sun, X Wu, S Liu… - Expert review of anti …, 2019 - Taylor & Francis
Introduction: Hand, foot, and mouth disease (HFMD) is a common viral childhood illness,
that has been a severe public health concern worldwide, particularly in the Asia-Pacific …

Recent development of enterovirus A vaccine candidates for the prevention of hand, foot, and mouth disease

CY Fang, CC Liu - Expert review of vaccines, 2018 - Taylor & Francis
Introduction: Hand, foot, and mouth disease (HFMD) is a childhood illness commonly
caused by enterovirus A. Enterovirus A71 (EV-A71) and coxsackievirus A16 (CV-A16) are …

A virus-like particle-based tetravalent vaccine for hand, foot, and mouth disease elicits broad and balanced protective immunity

W Zhang, W Dai, C Zhang, Y Zhou… - Emerging Microbes & …, 2018 - Taylor & Francis
Hand, foot, and mouth disease (HFMD) is an infectious disease that mainly affects infants
and children, causing considerable morbidity and mortality worldwide. HFMD is commonly …

A virus-like particle vaccine confers protection against enterovirus D68 lethal challenge in mice

W Dai, C Zhang, X Zhang, P Xiong, Q Liu, S Gong… - Vaccine, 2018 - Elsevier
Abstract Enterovirus D68 (EV-D68) is increasingly associated with severe acute respiratory
infection and acute flaccid myelitis (AFM) in children around the world. However, neither …

The immunogenicity and protection effect of an inactivated coxsackievirus A6, A10, and A16 vaccine against hand, foot, and mouth disease

H Lim, HJ In, JA Lee, JS Yoo, SW Lee, GT Chung… - Vaccine, 2018 - Elsevier
Coxsackievirus belongs to the Enterovirus genus of the Picornaviridae family and is one of
the major pathogens associated with human hand, foot, and mouth disease (HFMD) …

Efficacy of coxsackievirus A5 vaccine candidates in an actively immunized mouse model

WP Jin, J Lu, XY Zhang, J Wu, ZN Wei, JY Mai… - Journal of …, 2021 - Am Soc Microbiol
ABSTRACT Coxsackievirus A5 (CV-A5) has recently emerged as a main hand, foot, and
mouth disease (HFMD) pathogen. Following a large-scale vaccination campaign against …

VP2 residue N142 of coxsackievirus A10 is critical for the interaction with KREMEN1 receptor and neutralizing antibodies and the pathogenicity in mice

X Li, Z Liu, X Yan, Y Tian, K Liu, Y Zhao, J Shao… - PLoS …, 2023 - journals.plos.org
Coxsackievirus A10 (CVA10) has recently emerged as one of the major causative agents of
hand, foot, and mouth disease. CVA10 may also cause a variety of complications. No …

Protective efficacies of formaldehyde-inactivated whole-virus vaccine and antivirals in a murine model of coxsackievirus A10 infection

Z Zhang, Z Dong, J Li, MJ Carr, D Zhuang… - Journal of …, 2017 - Am Soc Microbiol
ABSTRACT Coxsackievirus A10 (CVA10) is one of the major pathogens associated with
hand, foot, and mouth disease (HFMD). CVA10 infection can cause herpangina and viral …

Coxsackievirus A10 atomic structure facilitating the discovery of a broad-spectrum inhibitor against human enteroviruses

J Chen, X Ye, XY Zhang, Z Zhu, X Zhang, Z Xu, Z Ding… - Cell discovery, 2019 - nature.com
Abstract Coxsackievirus A10 (CV-A10) belongs to the Enterovirus species A and is a
causative agent of hand, foot, and mouth disease. Here we present cryo-EM structures of CV …

Humoral and cellular immunogenicity and efficacy of a coxsackievirus A10 vaccine in mice

HH An, M Li, RL Liu, J Wu, SL Meng, J Guo… - Emerging Microbes & …, 2023 - Taylor & Francis
ABSTRACT Coxsackievirus A10 (CV-A10) has become one of the major pathogens of hand,
foot and mouth disease (HFMD), and studies on the vaccine and animal model of CV-A10 …