Multiple sclerosis (MS) is a chronic, immune-mediated demyelinating disease of the central
nervous system. Animal models of MS have been critical for elucidating MS pathological …

There are significant differences in the immune response and in the susceptibility to
autoimmune diseases among rodent strains. It would thus be expected that the contribution …

Early impairment of islet function and graft loss limit the success of allogeneic islet
transplantation. Nonspecific inflammatory events occurring at the transplant site immediately …

Experimental autoimmune encephalomyelitis (EAE) induced in the rat by active
immunization with myelin-oligodendrocyte-glycoprotein (MOG) is mediated by synergy …

The cellular constituents of the blood–brain barrier (BBB) must make finely tuned, regulatory
responses to maintain microvascular homeostasis. The mechanisms by which this task is …

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the CNS. Activated
microglia/macrophages play a key role in the immunopathogenesis of MS and its …

Worldwide, breast cancer is the second leading cause of cancer death among women and
the third most common cancer. Although our understanding of the molecular basis of this …

In the present research, the effect of clove essential oil (CO) and its major constituent,
eugenol, formulated in water-based microemulsions, was studied on fatty liver and …

Experimental autoimmune encephalomyelitis (EAE) in rats is typically a brief and
monophasic disease with sparse demyelination. However, inbred DA rats develop a …

Regulation of the immune response is critical to homeostasis. While innate immunity can
influence the development of adaptive immune responses, its role in regulation is less well …