Curcumin is widely consumed in Asia either as turmeric directly or as one of the culinary
ingredients in food recipes. The benefits of curcumin in different organ systems have been …

Trimethylamine lyases are expressed in a wide range of intestinal microbiota which
metabolize dietary nutrients like choline, betaine, and L-carnitine to form trimethylamine …

Background: Renin-angiotensin system (RAS) inhibitors have been suggested as protective
agents in Parkinson's disease (PD). However, epidemiological evidence on the association …

Phosphodiesterases (PDE) are a diverse family of enzymes (11 isoforms so far identified)
responsible for the degradation of cyclic adenosine monophosphate (cAMP) and cyclic …

Neuroprotective effects of curcumin have been shown in previous studies. This updated
systematic review of clinical trials aimed to investigate the effect of curcumin on neurological …

Recent researches showed that nucleotide-binding domain and leucine-rich repeat protein
3 (NLRP3) inflammasome inhibition exerted dopaminergic neuroprotection in cellular or …

The RAS (renin-angiotensin system) is the part of the endocrine system that plays a prime
role in the control of essential hypertension. Since the discovery of brain RAS in the …

The past few decades have seen an increased emphasis on the involvement of the
mitochondrial-associated membrane (MAM) in various neurodegenerative diseases …

Rotenone is an insecticide that generates oxidative stress in the CNS and induces
locomotor dysfunction and neurodegeneration in rodents. Biochanin A [BioA] is an …

Huntington's disease (HD) is an inherited devastating neurodegenerative disorder with
disabling motor and cognitive derangements that hinder the patients from performing their …