Migraine: disease characterisation, biomarkers, and precision medicine

M Ashina, GM Terwindt, MAM Al-Karagholi, I De Boer… - The Lancet, 2021 - thelancet.com
Migraine is a disabling neurological disorder, diagnosis of which is based on clinical criteria.
A shortcoming of these criteria is that they do not fully capture the heterogeneity of migraine …

Migraine: from pathophysiology to treatment

F Puledda, EM Silva, K Suwanlaong, PJ Goadsby - Journal of Neurology, 2023 - Springer
Migraine is an extremely disabling, common neurological disorder characterized by a
complex neurobiology, involving a series of central and peripheral nervous system areas …

Pathophysiology of migraine: a disorder of sensory processing

PJ Goadsby, PR Holland… - Physiological …, 2017 - journals.physiology.org
Plaguing humans for more than two millennia, manifest on every continent studied, and with
more than one billion patients having an attack in any year, migraine stands as the sixth …

Mechanisms of migraine as a chronic evolutive condition

AP Andreou, L Edvinsson - The journal of headache and pain, 2019 - Springer
Understanding the mechanisms of migraine remains challenging as migraine is not a static
disorder, and even in its episodic form migraine remains an “evolutive” chronic condition …

An update on migraine: current understanding and future directions

F Puledda, R Messina, PJ Goadsby - Journal of neurology, 2017 - Springer
Migraine is a common brain disorder with high disability rates which involves a series of
abnormal neuronal networks, interacting at different levels of the central and peripheral …

Transcutaneous auricular vagus nerve stimulation (taVNS) for migraine: an fMRI study

Y Zhang, Y Huang, H Li, Z Yan, Y Zhang… - Regional Anesthesia & …, 2021 - rapm.bmj.com
Background Dysfunction of the thalamocortical connectivity network is thought to underlie
the pathophysiology of the migraine. This current study aimed to explore the thalamocortical …

Current understanding of thalamic structure and function in migraine

S Younis, A Hougaard, R Noseda, M Ashina - Cephalalgia, 2019 - journals.sagepub.com
Objective To review and discuss the literature on the role of thalamic structure and function
in migraine. Discussion The thalamus holds an important position in our understanding of …

Increased amplitude of thalamocortical low-frequency oscillations in patients with migraine

DJ Hodkinson, SL Wilcox, R Veggeberg… - Journal of …, 2016 - Soc Neuroscience
For many years, neurobiological theories have emphasized the importance of neuronal
oscillations in the emergence of brain function. At the same time, clinical studies have shown …

The genetic landscape of basal ganglia and implications for common brain disorders

S Bahrami, K Nordengen, J Rokicki, AA Shadrin… - Nature …, 2024 - nature.com
The basal ganglia are subcortical brain structures involved in motor control, cognition, and
emotion regulation. We conducted univariate and multivariate genome-wide association …

Thalamo-cortical network activity during spontaneous migraine attacks

G Coppola, A Di Renzo, E Tinelli, C Di Lorenzo… - Neurology, 2016 - AAN Enterprises
Objective: We used MRI to search for changes in thalamo-cortical networks and thalamic
microstructure during spontaneous migraine attacks by studying at the same time structure …