SARS-CoV-2 variants, vaccines, and host immunity

P Mistry, F Barmania, J Mellet, K Peta… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new beta coronavirus
that emerged at the end of 2019 in the Hubei province of China. SARS-CoV-2 causes …

The impact of evolving SARS-CoV-2 mutations and variants on COVID-19 vaccines

G McLean, J Kamil, B Lee, P Moore, TF Schulz, A Muik… - MBio, 2022 - Am Soc Microbiol
The emergence of several new variants of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) in recent months has raised concerns around the potential impact on …

A systematic review of coronavirus disease 2019 vaccine efficacy and effectiveness against severe acute respiratory syndrome coronavirus 2 infection and disease

MM Higdon, B Wahl, CB Jones… - Open Forum …, 2022 - academic.oup.com
Billions of doses of coronavirus disease 2019 (COVID-19) vaccines have been administered
globally, dramatically reducing severe acute respiratory syndrome coronavirus 2 (SARS …

COVID-19 vaccine booster: to boost or not to boost

R Shekhar, I Garg, S Pal, S Kottewar… - Infectious disease …, 2021 - mdpi.com
Developing safe and effective vaccines against severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) at a breakneck speed has been an exceptional human …

A systematic review of COVID-19 vaccine efficacy and effectiveness against SARS-CoV-2 infection and disease

MM Higdon, B Wahl, CB Jones, JG Rosen, SA Truelove… - MedRXiv, 2021 - medrxiv.org
Billions of doses of COVID-19 vaccines have been administered globally, dramatically
reducing SARS-CoV-2 incidence and severity in some settings. Many studies suggest …

[HTML][HTML] Cohort study of Covid-19 vaccine effectiveness among healthcare workers in Finland, December 2020-October 2021

E Poukka, U Baum, AA Palmu, TO Lehtonen, H Salo… - Vaccine, 2022 - Elsevier
Recently, Covid-19 vaccine effectiveness has decreased especially against mild disease
due to emergence of the Delta variant and waning protection. In this register-based study …

Early immunogenicity and safety of the third dose of BNT162b2 messenger RNA coronavirus disease 2019 vaccine among adults older than 60 years: real-world …

M Gilboa, M Mandelboim, V Indenbaum… - The Journal of …, 2022 - academic.oup.com
Background Despite high vaccine coverage, an increase in breakthrough coronavirus
disease 2019 (COVID-19) infections, prompted administration of a third BNT162b2 dose to …

Increased B cell selection stringency in germinal centers can explain improved COVID-19 vaccine efficacies with low dose prime or delayed boost

AK Garg, S Mittal, P Padmanabhan, R Desikan… - Frontiers in …, 2021 - frontiersin.org
The efficacy of COVID-19 vaccines appears to depend in complex ways on the vaccine
dosage and the interval between the prime and boost doses. Unexpectedly, lower dose …

Mechanistic models of COVID-19: insights into disease progression, vaccines, and therapeutics

R Desikan, P Padmanabhan, AM Kierzek… - International Journal of …, 2022 - Elsevier
The COVID-19 pandemic has severely impacted health systems and economies worldwide.
Significant global efforts are therefore ongoing to improve vaccine efficacies, optimize …

A case of exacerbation of subclinical hyperthyroidism after first administration of BNT162b2 mRNA COVID-19 vaccine

K Yamamoto, T Mashiba, K Takano, T Suzuki, M Kami… - Vaccines, 2021 - mdpi.com
COVID-19 vaccines are the most critical measure for controlling the COVID-19 pandemic;
however, we have little information on their complications. We experienced a case of a …