Metastasis is the most complex and deadly event. Tumor-stromal interface is a place where
invasion of tumor cells in the form of single-cell or collective migration occurs, with the latter …

The Golgi apparatus plays a central role in normal cell physiology by promoting cell survival,
facilitating proliferation, and enabling cell-cell communication and migration. These roles …

The Golgi apparatus is at the center of protein processing and trafficking in normal cells.
Under pathological conditions, such as in cancer, aberrant Golgi dynamics alter the tumor …

Hepatitis B virus (HBV) infection is the predominant causes of hepatocellular carcinoma
(HCC). HBV X protein (HBx), as the most frequently integrated viral gene sequence …

Abstract Background Long non-coding RNAs (lncRNAs) play a critical role in the
pathogenesis of hypoxic pulmonary hypertension (HPH). The role of N7-methylguanosine …

Abstract Background Bladder cancer (BCa) is a fatal form of cancer worldwide associated
with a poor prognosis. Identifying novel drivers of growth and metastasis hold therapeutic …

Abstract Background Histone deacetylases (HDACs) engage in the regulation of various
cellular processes by controlling global gene expression. The dysregulation of HDACs leads …

Lung cancer is a highly aggressive and metastatic disease responsible for approximately
25% of all cancer-related deaths in the United States. Using high-throughput in vitro and in …

KDEL receptors (KDELRs) are ubiquitous seven-transmembrane domain proteins encoded
by three mammalian genes. They bind to and retro-transport endoplasmic reticulum (ER) …

Background This review discusses the impact of mono or combination therapy of immune
checkpoint inhibitor (ICI) therapy in non-small cell lung cancer (NSCLC) patients, comparing …