New developments of the principle of vinylogy as applied to π-extended enolate-type donor systems
The principle of vinylogy states that the electronic effects of a functional group in a molecule
are possibly transmitted to a distal position through interposed conjugated multiple bonds …
are possibly transmitted to a distal position through interposed conjugated multiple bonds …
Organocatalytic asymmetric vinylogous Michael reactions
Y Yin, Z Jiang - ChemCatChem, 2017 - Wiley Online Library
Since RC Fuson formulated the principle of vinylogy, this platform has been extensively
developed through combining diverse predominant chemical transformations. Among them …
developed through combining diverse predominant chemical transformations. Among them …
Organocatalyzed Asymmetric 1,6-Conjugate Addition of para-Quinone Methides with Dicyanoolefins
X Li, X Xu, W Wei, A Lin, H Yao - Organic letters, 2016 - ACS Publications
A chiral thiourea catalyzed asymmetric 1, 6-conjugate addition of para-quinone methides
with dicyanoolefins has been developed. The reaction provided an efficient approach to the …
with dicyanoolefins has been developed. The reaction provided an efficient approach to the …
Central-to-Axial Chirality: Asymmetric Organocatalytic Synthesis of Axially Chiral Chalcones via Exocyclic Dihydronaphthalenes
Asymmetric synthesis of an unprecedented exocyclic dihydronaphthalene and an axially
chiral naphthalene chalcone has been disclosed. Good to excellent asymmetric induction is …
chiral naphthalene chalcone has been disclosed. Good to excellent asymmetric induction is …
Ag (i)-catalyzed asymmetric (2+ 4) annulation reaction of 5-alkenyl thiazolones: synthesis of enantioenriched spiro [cyclohexenamines-thiazolones]
K Choudhary, AS Deshpande, VK Singh - Chemical Communications, 2024 - pubs.rsc.org
The first metal-catalyzed (2+ 4) annulation of 5-alkenyl thiazolones and α, α-
dicyanoalkylidenes has been developed via vinylogous Michael/cyclization/isomerization …
dicyanoalkylidenes has been developed via vinylogous Michael/cyclization/isomerization …
Asymmetric Synthesis of Spiro-3, 3′-cyclopropyl Oxindoles via Vinylogous Michael Initiated Ring Closure Reaction
A novel organocatalytic cascade approach for the synthesis of spiro-cyclopropyl oxindole
derivatives has been developed. The methodology is based on asymmetric vinylogous …
derivatives has been developed. The methodology is based on asymmetric vinylogous …
Organocatalytic enantioselective vinylogous Michael-aldol cascade for the synthesis of spirocyclic compounds
Enantioselective synthesis of pyrazolone-fused spirocyclohexenols by the secondary amine-
catalyzed cascade reaction of α, β-unsaturated aldehydes with α-arylidene pyrazolinones is …
catalyzed cascade reaction of α, β-unsaturated aldehydes with α-arylidene pyrazolinones is …
Enantioselective Construction of Pyridine N-Oxides Featuring 2,3-Dihydrofuran Motifs via Phosphine-Catalyzed [4 + 1]-Annulation of 2-Enoylpyridine N-Oxides with …
The first example of phosphine-catalyzed enantioselective [4+ 1] annulations between 2-
enoylpyridine N-oxides and Morita–Baylis–Hillman carbonates is described. When 1, 2-bis …
enoylpyridine N-oxides and Morita–Baylis–Hillman carbonates is described. When 1, 2-bis …
Bismuth Triflate-Catalyzed Vinylogous Nucleophilic 1,6-Conjugate Addition of para-Quinone Methides with 3-Propenyl-2-silyloxyindoles
KX Xie, ZP Zhang, X Li - Organic letters, 2017 - ACS Publications
A highly diastereoselective vinylogous nucleophilic 1, 6-conjugate addition reaction of para-
quinone methides with 3-propenyl-2-silyloxyindoles by a bismuth triflate catalyst has been …
quinone methides with 3-propenyl-2-silyloxyindoles by a bismuth triflate catalyst has been …
Effective asymmetric vinylogous Mannich reaction of isatin imines with α, α-dicyanoolefins in the presence of a simple chiral amide phosphonium bifunctional phase …
C Cheng, X Lu, L Ge, J Chen, W Cao, X Wu… - Organic Chemistry …, 2017 - pubs.rsc.org
An asymmetric vinylogous Mannich reaction between α, α-dicyanoolefins and N-Boc isatin
imines has been developed by employing 1 mol% bifunctional amide phosphonium salt as a …
imines has been developed by employing 1 mol% bifunctional amide phosphonium salt as a …