Rotaviruses: From pathogenesis to disease control—A critical review

CA Omatola, AO Olaniran - Viruses, 2022 - mdpi.com
Since their first recognition in human cases about four decades ago, rotaviruses have
remained the leading cause of acute severe dehydrating diarrhea among infants and young …

Rotavirus in developing countries: Molecular diversity, epidemiological insights, and strategies for effective vaccination

A Sadiq, J Khan - Frontiers in Microbiology, 2024 - frontiersin.org
Rotavirus (RV) causes the loss of numerous children's lives worldwide each year, and this
burden is particularly heavy in low-and lower-middle-income countries where access to …

Genetic heterogeneity of group A rotaviruses: a review of the evolutionary dynamics and implication on vaccination

CA Omatola, AO Olaniran - Expert Review of Anti-infective Therapy, 2022 - Taylor & Francis
Introduction Human rotavirus remains a major etiology of acute gastroenteritis among under
5-year children worldwide despite the availability of oral vaccines. The genetic instability of …

Epidemiology and pre-vaccine burden of rotavirus diarrhea in Democratic Republic of Congo (DRC): Results of sentinel surveillance, 2009–2019

CL Lungayo, RM Burke, A Cikomola, E Mukamba… - Vaccine, 2022 - Elsevier
Abstract Introduction Since August 2009, the Democratic Republic of Congo (DRC) has
implemented sentinel site surveillance for rotavirus gastroenteritis. Limited hospital studies …

Isolation and characterization of distinct Rotavirus A in bat and rodent hosts

M Kishimoto, M Kajihara, K Tabata, Y Itakura… - Journal of …, 2023 - Am Soc Microbiol
Rotavirus A (RVA) causes diarrheal disease in humans and various animals. Recent studies
have identified bat and rodent RVAs with evidence of zoonotic transmission and genome …

[HTML][HTML] Molecular epidemiology, genetic diversity, and vaccine availability of viral acute gastroenteritis in the middle East and North Africa (MENA) region

I Elbashir, NF Aldoos, S Mathew, AA Al Thani… - Journal of Infection and …, 2022 - Elsevier
Acute gastroenteritis is the cause of considerable mortality and morbidity worldwide,
particularly among children under five years in underdeveloped countries. Most acute …

Single domain antibodies from camelids in the treatment of microbial infections

H De Greve, A Fioravanti - Frontiers in Immunology, 2024 - frontiersin.org
Infectious diseases continue to pose significant global health challenges. In addition to the
enduring burdens of ailments like malaria and HIV, the emergence of nosocomial outbreaks …

Genetic diversity of enteric viruses responsible of gastroenteritis in urban and rural Burkina Faso

AOR Badjo, S Niendorf, S Jacobsen… - PLOS Neglected …, 2024 - journals.plos.org
Background Viral gastrointestinal infections remain a major public health concern in
developing countries. In Burkina Faso, there are very limited updated data on the circulating …

Phylogenetic analysis of VP7 and VP4 genes of the most predominant human group A rotavirus G12 identified in children with acute gastroenteritis in Himachal …

S Gupta, M Gauhar, P Bubber… - Journal of Medical …, 2021 - Wiley Online Library
G12 strains are now considered to be the sixth most prevalent human rotaviruses globally.
India has introduced rotavirus vaccine Rotavac® into the national immunization program in …

Characterization of Rotavirus Strains Responsible for Breakthrough Diarrheal Diseases among Zambian Children Using Whole Genome Sequencing

I Mwape, NM Laban, K Chibesa, A Moono, S Silwamba… - Vaccines, 2023 - mdpi.com
The occurrence of rotavirus (RV) infection among vaccinated children in high-burden
settings poses a threat to further disease burden reduction. Genetically altered viruses have …