Corneal neovascularization

MP Nicholas, N Mysore - Experimental eye research, 2021 - Elsevier
The optical clarity of the cornea is essential for maintaining good visual acuity. Corneal
neovascularization, which is a major cause of vision loss worldwide, leads to corneal …

Pterygium—the good, the bad, and the ugly

SI Van Acker, B Van den Bogerd, M Haagdorens… - Cells, 2021 - mdpi.com
Pterygium is a multifaceted pathology that displays apparent conflicting characteristics:
benign (eg, self-limiting and superficial), bad (eg, proliferative and potentially recurrent) and …

Corneal gene therapy: structural and mechanistic understanding

R Kumar, NR Sinha, RR Mohan - The Ocular Surface, 2023 - Elsevier
Cornea, a dome-shaped and transparent front part of the eye, affords 2/3rd refraction and
barrier functions. Globally, corneal diseases are the leading cause of vision impairment …

The role of IL-6-174 G/C polymorphism and intraocular IL-6 levels in the pathogenesis of ocular diseases: a systematic review and meta-analysis

ZS Ulhaq, GV Soraya, Budu, LR Wulandari - Scientific reports, 2020 - nature.com
Abstract Interleukin-6 (IL-6) is one of the key regulators behind the inflammatory and
pathological process associated with ophthalmic diseases. The role of IL-6-174 G/C …

Characteristics and recurrence of pterygium in Saudi Arabia: a single center study with a long follow‐up

W Alsarhani, S Alshahrani, M Showail, N Alhabdan… - BMC …, 2021 - Springer
Background This study described the clinical features of patients with pterygium and
analyzed the recurrence rate of conjunctival autografting alone, conjunctival autografting …

Biomarkers in the occurrence and development of pterygium

S He, Z Wu - Ophthalmic Research, 2022 - karger.com
Pterygium is a kind of common conjunctival degeneration. The pathogenesis of pterygium is
complex, and various biomarkers provide new targets for treatment and prognosis …

Evaluation of lymphotoxin-alpha in pterygium and diagnostic value in active and inactive pterygium states

G Lan, X Fang, Y Zhong, S Luo, X Xiao, Z Xie, L Luo… - Scientific Reports, 2024 - nature.com
To explore the correlation between tear LT-a, pterygium status, and dry eye indicators. We
established a diagnostic model to evaluate active pterygium. A retrospective study was …

[HTML][HTML] Anti-inflammatory effects of α-humulene and β-caryophyllene on pterygium fibroblasts

MMH Viveiros, MG Silva, JGM da Costa… - International Journal …, 2022 - ncbi.nlm.nih.gov
AIM To investigate the anti-inflammatory effects of the sesquiterpenes α-humulene and β-
caryophyllene on pterygium fibroblasts. METHODS Primary cultures of pterygium fibroblasts …

A Systematic Review of Tear Vascular Endothelial Growth Factor and External Eye Diseases

J Chan, G Lim, R Lee, L Tong - International Journal of Molecular …, 2024 - mdpi.com
We aim to summarize the current evidence of Vascular endothelial growth factors (VEGF) s
in external eye diseases and determine whether serum and plasma VEGF levels are …

Effect of a topical nonsteroidal anti-inflammatory drug (0.1% pranoprofen) on VEGF and COX-2 expression in primary pterygium

B Yao, F Wang, X Zhao, B Wang, X Yue… - Frontiers in …, 2021 - frontiersin.org
Purpose: To evaluate the effect of a topical nonsteroidal anti-inflammatory drug (0.1%
pranoprofen) on the expression of VEGF and Cox-2 in primary pterygium. Methods: This was …