Differences in alpha diversity of gut microbiota in neurological diseases

Z Li, J Zhou, H Liang, L Ye, L Lan, F Lu… - Frontiers in …, 2022 - frontiersin.org
Background Neurological diseases are difficult to diagnose in time, and there is currently a
lack of effective predictive methods. Previous studies have indicated that a variety of …

Changes in gut microbiota and multiple sclerosis: a systematic review

A Ordoñez-Rodriguez, P Roman… - International Journal of …, 2023 - mdpi.com
Introduction: Multiple sclerosis (MS) is a chronic inflammatory neurodegenerative disease
mediated by autoimmune reactions against myelin proteins and gangliosides in the grey …

Gut immune cell trafficking: inter-organ communication and immune-mediated inflammation

S Zundler, C Günther, AE Kremer, MM Zaiss… - Nature Reviews …, 2023 - nature.com
Immune cell trafficking is a complex and tightly regulated process that is indispensable for
the body's fight against pathogens. However, it is also increasingly acknowledged that …

Contribution of gut-derived T cells to extraintestinal autoimmune diseases

Q Wang, Y Wu, Q Lu, M Zhao - Trends in Immunology, 2024 - cell.com
The mammalian intestine harbors abundant T cells with high motility, where these cells can
affect both intestinal and extraintestinal disorders. Growing evidence shows that gut-derived …

Probiotics and commensal gut microbiota as the effective alternative therapy for multiple sclerosis patients treatment

A Dziedzic, J Saluk - International Journal of Molecular Sciences, 2022 - mdpi.com
The gut-brain axis (GBA) refers to the multifactorial interactions between the intestine
microflora and the nervous, immune, and endocrine systems, connecting brain activity and …

Interaction of the gut microbiome and immunity in multiple sclerosis: impact of diet and immune therapy

SK Yadav, K Ito, S Dhib-Jalbut - International journal of molecular …, 2023 - mdpi.com
The bidirectional communication between the gut and central nervous system (CNS)
through microbiota is known as the microbiota–gut–brain axis. The brain, through the enteric …

Identification of commensal gut microbiota signatures as predictors of clinical severity and disease progression in multiple sclerosis

TL Montgomery, Q Wang, A Mirza, D Dwyer, Q Wu… - Scientific Reports, 2024 - nature.com
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system and a
leading cause of neurological disability in young adults. Clinical presentation and disease …

Meta-analysis identifies common gut microbiota associated with multiple sclerosis

Q Lin, Y Dorsett, A Mirza, H Tremlett, L Piccio… - Genome Medicine, 2024 - Springer
Background Previous studies have identified a diverse group of microbial taxa that differ
between patients with multiple sclerosis (MS) and the healthy population. However …

Fecal Lcn-2 level is a sensitive biological indicator for gut dysbiosis and intestinal inflammation in multiple sclerosis

SK Yadav, N Ito, JE Mindur, H Kumar… - Frontiers in …, 2022 - frontiersin.org
Multiple Sclerosis (MS) has been reported to be associated with intestinal inflammation and
gut dysbiosis. To elucidate the underlying biology of MS-linked gut inflammation, we …

Targeting gut microbiota: new therapeutic opportunities in multiple sclerosis

D Kujawa, L Laczmanski, S Budrewicz… - Gut …, 2023 - Taylor & Francis
Multiple sclerosis (MS) causes long-lasting, multifocal damage to the central nervous
system. The complex background of MS is associated with autoimmune inflammation and …