Thrombolysis for acute ischaemic stroke: current status and future perspectives
Alteplase is currently the only approved thrombolytic agent for treatment of acute ischaemic
stroke, but interest is burgeoning in the development of new thrombolytic agents for systemic …
stroke, but interest is burgeoning in the development of new thrombolytic agents for systemic …
Advances in acute ischemic stroke therapy
Y Xiong, AK Wakhloo, M Fisher - Circulation research, 2022 - Am Heart Assoc
The treatment of acute ischemic stroke continues to advance. The mainstay of treatment
remains intravenous thrombolysis with alteplase. Recent studies demonstrated that later …
remains intravenous thrombolysis with alteplase. Recent studies demonstrated that later …
[HTML][HTML] Prospective, multicenter, controlled trial of mobile stroke units
Abstract Background Mobile stroke units (MSUs) are ambulances with staff and a computed
tomographic scanner that may enable faster treatment with tissue plasminogen activator (t …
tomographic scanner that may enable faster treatment with tissue plasminogen activator (t …
Comparison of tenecteplase with alteplase for the early treatment of ischaemic stroke in the Melbourne Mobile Stroke Unit (TASTE-A): a phase 2, randomised, open …
Summary Background Mobile stroke units (MSUs) equipped with a CT scanner reduce time
to thrombolytic treatment and improve patient outcomes. We tested the hypothesis that …
to thrombolytic treatment and improve patient outcomes. We tested the hypothesis that …
Pharmacological brain cytoprotection in acute ischaemic stroke—renewed hope in the reperfusion era
M Fisher, SI Savitz - Nature Reviews Neurology, 2022 - nature.com
For over 40 years, attempts to develop treatments that protect neurons and other brain cells
against the cellular and biochemical consequences of cerebral ischaemia in acute …
against the cellular and biochemical consequences of cerebral ischaemia in acute …
Treatments in ischemic stroke: current and future
MG Mosconi, M Paciaroni - European neurology, 2022 - karger.com
Abstract Background and Aim: Despite progress made over the last 30 years, stroke is still a
leading cause of disability and mortality; likewise, its burden is expected to increase over the …
leading cause of disability and mortality; likewise, its burden is expected to increase over the …
An overview of telehealth in the management of cardiovascular disease: a scientific statement from the American Heart Association
Telehealth enables the remote delivery of health care through telecommunication
technologies and has substantially affected the evolving medical landscape. The COVID-19 …
technologies and has substantially affected the evolving medical landscape. The COVID-19 …
Comparison of mobile stroke unit with usual care for acute ischemic stroke management: a systematic review and meta-analysis
Importance So far, uncertainty remains as to whether there is sufficient cumulative evidence
that mobile stroke unit (MSU; specialized ambulance equipped with computed tomography …
that mobile stroke unit (MSU; specialized ambulance equipped with computed tomography …
Association between use of a flying intervention team vs patient interhospital transfer and time to endovascular thrombectomy among patients with acute ischemic …
GJ Hubert, ND Hubert, C Maegerlein, F Kraus… - JAMA, 2022 - jamanetwork.com
Importance The benefit of endovascular thrombectomy (EVT) for acute ischemic stroke is
highly time-dependent, and it is challenging to expedite treatment for patients in remote …
highly time-dependent, and it is challenging to expedite treatment for patients in remote …
Mobile stroke units: evidence, gaps, and next steps
Mobile stroke units (MSUs) are specialized ambulances equipped with the personnel,
equipment, and imaging capability to diagnose and treat acute stroke in the prehospital …
equipment, and imaging capability to diagnose and treat acute stroke in the prehospital …