The Aminoacyl-tRNA Synthetases (aaRSs) are an evolutionarily ancient family of enzymes
that catalyze the esterification reaction linking a transfer RNA (tRNA) with its cognate amino …

Idiopathic inflammatory myopathies are a group of rare, immune-mediated diseases that
primarily affect the skeletal muscle but can also involve other organs such as the lungs, skin …

Update on autoantibodies and related biomarkers in autoimmun... : Current Opinion in
Rheumatology Update on autoantibodies and related biomarkers in autoimmune inflammatory …

Systemic sclerosis (SSc) is a progressive, multiorgan disease with limited treatment options.
Although a recent proof-of-concept study using romilkimab or SAR156597, a bispecific IL …

Efzofitimod is a first-in-class biologic immunomodulator based on a naturally occurring
splice variant of histidyl-tRNA synthetase (HARS) that binds to neuropilin-2 (NRP2) …

Antisynthetase syndrome (ASSD) is an autoimmune disease characterized by circulating
autoantibodies against one of eight aminoacyl-tRNA synthetases (aaRSs). Although these …

Anti-synthetase syndrome (ASS) is a rare autoimmune disease. Since the knowledge of ASS
remains limited, we conducted the retrospective study aiming to describe clinical …

The authors identified different pitfalls in the criteria and suggested actions that a possible
revision should take to overa come them. The focus is surely well directed, but we believe …

Objective Anti‐synthetase syndrome (ASSD) is a rare systemic autoimmune rheumatic
disease (SARD) with significant heterogeneity and no shared classification criteria. We …

Autoantibodies are important for the diagnosis of autoimmune interstitial lung disease (ILD).
Standard immunoassays have limitations, including their qualitative nature and/or a narrow …