Ferroptosis is a mechanism of regulated necrotic cell death characterized by iron-
dependent, lipid peroxidation-driven membrane destruction that can be inhibited by …

Reprogramming of cellular metabolism is a hallmark of cancer. Cancer cells undergo
metabolic adaptations to maintain tumorigenicity and survive under the attack of immune …

Long-chain fatty acyl-coenzyme As (CoAs) are critical regulatory molecules and metabolic
intermediates. The initial step in their synthesis is the activation of fatty acids by one of 13 …

The most common omega-3 fatty acids contain 18–22 carbons and a signature double bond
at the third position from the methyl (or n, or omega) end of the molecule. These fatty acids …

The stratum corneum as the outermost epidermal layer protects against exsiccation and
infection. Both the underlying cornified envelope (CE) and the intercellular lipid matrix …

The lactating bovine mammary gland is a formidable triacylglycerol-synthesizing machine
and, as such, represents an ideal model for studying putative functions of distinct isoforms of …

Increased fructose intake from sugar-sweetened beverages and highly processed sweets is
a well-recognized risk factor for the development of obesity and its complications. Fructose …

Context: The human adrenal zona fasciculata (ZF) and zona reticularis (ZR) are responsible
for the production of cortisol and 19-carbon steroids (often called adrenal androgens) …

The de novo synthesis of fatty acids has emerged as a therapeutic target for various
diseases, including cancer. Because cancer cells are intrinsically buffered to combat …

Abstract Peripheral serotonin (5-hydroxytryptamine: 5-HT) synthesized in the intestine by
enterochromaffin cells (ECs), plays an important role in the regulation of peristaltic of the gut …