Chromatin remodeler Activity-Dependent Neuroprotective Protein (ADNP) contributes to syndromic autism
CP D'Incal, KE Van Rossem, K De Man, A Konings… - Clinical …, 2023 - Springer
Background Individuals affected with autism often suffer additional co-morbidities such as
intellectual disability. The genes contributing to autism cluster on a relatively limited number …
intellectual disability. The genes contributing to autism cluster on a relatively limited number …
High mobility group box 1 in human cancer
BL Rapoport, HC Steel, AJ Theron, L Heyman, T Smit… - Cells, 2020 - mdpi.com
High mobility group box 1 (HMGB1) is an extremely versatile protein that is located
predominantly in the nucleus of quiescent eukaryotic cells, where it is critically involved in …
predominantly in the nucleus of quiescent eukaryotic cells, where it is critically involved in …
Bioinformatics and machine learning approach identifies potential drug targets and pathways in COVID-19
Abstract Current coronavirus disease-2019 (COVID-19) pandemic has caused massive loss
of lives. Clinical trials of vaccines and drugs are currently being conducted around the world; …
of lives. Clinical trials of vaccines and drugs are currently being conducted around the world; …
[HTML][HTML] Identification of molecular signatures and pathways to identify novel therapeutic targets in Alzheimer's disease: Insights from a systems biomedicine …
MR Rahman, T Islam, T Zaman, M Shahjaman… - Genomics, 2020 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by the
accumulation of amyloid plaques and neurofibrillary tangles in the brain. However, there are …
accumulation of amyloid plaques and neurofibrillary tangles in the brain. However, there are …
Computational identification of host genomic biomarkers highlighting their functions, pathways and regulators that influence SARS-CoV-2 infections and drug …
The pandemic threat of COVID-19 has severely destroyed human life as well as the
economy around the world. Although, the vaccination has reduced the outspread, but …
economy around the world. Although, the vaccination has reduced the outspread, but …
Network-based approach to identify molecular signatures and therapeutic agents in Alzheimer's disease
Alzheimer's disease (AD) is a dynamic degeneration of the brain with progressive dementia.
Considering the uncertainties in its molecular mechanism, in the present study, we …
Considering the uncertainties in its molecular mechanism, in the present study, we …
Integrated analysis of multi-omics data for the discovery of biomarkers and therapeutic targets for colorectal cancer
N Zafari, P Bathaei, M Velayati… - Computers in Biology …, 2023 - Elsevier
The considerable burden of colorectal cancer and the rising trend in young adults
emphasize the necessity of understanding its underlying mechanisms, providing new …
emphasize the necessity of understanding its underlying mechanisms, providing new …
Robust identification of common genomic biomarkers from multiple gene expression profiles for the prognosis, diagnosis, and therapies of pancreatic cancer
Pancreatic cancer (PC) is one of the leading causes of cancer-related death globally. So,
identification of potential molecular signatures is required for diagnosis, prognosis, and …
identification of potential molecular signatures is required for diagnosis, prognosis, and …
[HTML][HTML] Detection of molecular signatures and pathways shared in inflammatory bowel disease and colorectal cancer: a bioinformatics and systems biology approach
Emerging evidence indicates IBD is a risk factor for the increasing incidence of colorectal
cancer (CRC) development. We used a system biology approach to identify common …
cancer (CRC) development. We used a system biology approach to identify common …
Exploring core genes by comparative transcriptomics analysis for early diagnosis, prognosis, and therapies of colorectal cancer
Simple Summary Colorectal cancer (CRC) is a complex disease that has a high mortality
rate. This study explored CRC-related core genes (CGs) from multiple microarray gene …
rate. This study explored CRC-related core genes (CGs) from multiple microarray gene …