Quantitative magnetic resonance imaging towards clinical application in multiple sclerosis
Quantitative MRI provides biophysical measures of the microstructural integrity of the CNS,
which can be compared across CNS regions, patients, and centres. In patients with multiple …
which can be compared across CNS regions, patients, and centres. In patients with multiple …
Probing myelin content of the human brain with MRI: A review
Rapid and efficient transmission of electric signals among neurons of vertebrates is ensured
by myelin‐insulating sheaths surrounding axons. Human cognition, sensation, and motor …
by myelin‐insulating sheaths surrounding axons. Human cognition, sensation, and motor …
[HTML][HTML] Model-informed machine learning for multi-component T2 relaxometry
Recovering the T 2 distribution from multi-echo T 2 magnetic resonance (MR) signals is
challenging but has high potential as it provides biomarkers characterizing the tissue micro …
challenging but has high potential as it provides biomarkers characterizing the tissue micro …
Widespread intra‐axonal signal fraction abnormalities in bipolar disorder from multicompartment diffusion MRI: Sensitivity to diagnosis, association with clinical …
EJ Canales‐Rodríguez, N Verdolini… - Human Brain …, 2023 - Wiley Online Library
Despite diffusion tensor imaging (DTI) evidence for widespread fractional anisotropy (FA)
reductions in the brain white matter of patients with bipolar disorder, questions remain …
reductions in the brain white matter of patients with bipolar disorder, questions remain …
Harnessing myelin water fraction as an imaging biomarker of human cerebral aging, neurodegenerative diseases, and risk factors influencing myelination: A review
Myelin water fraction (MWF) imaging has emerged as a promising magnetic resonance
imaging (MRI) biomarker for investigating brain function and composition. This …
imaging (MRI) biomarker for investigating brain function and composition. This …
[HTML][HTML] Bundle myelin fraction (BMF) mapping of different white matter connections using microstructure informed tractography
To date, we have scarce information about the relative myelination level of different fiber
bundles in the human brain. Indirect evidence comes from postmortem histology data but …
bundles in the human brain. Indirect evidence comes from postmortem histology data but …
[HTML][HTML] Comparison of non-parametric T2 relaxometry methods for myelin water quantification
Multi-component T 2 relaxometry allows probing tissue microstructure by assessing
compartment-specific T 2 relaxation times and water fractions, including the myelin water …
compartment-specific T 2 relaxation times and water fractions, including the myelin water …
Systematic review of reconstruction techniques for accelerated quantitative MRI
Purpose To systematically review the techniques that address undersampling artifacts in
accelerated quantitative magnetic resonance imaging (qMRI). Methods A literature search …
accelerated quantitative magnetic resonance imaging (qMRI). Methods A literature search …
[HTML][HTML] Age-and gender-related differences in brain tissue microstructure revealed by multi-component T2 relaxometry
In spite of extensive work, inconsistent findings and lack of specificity in most neuroimaging
techniques used to examine age-and gender-related patterns in brain tissue microstructure …
techniques used to examine age-and gender-related patterns in brain tissue microstructure …
[HTML][HTML] Revisiting the T2 spectrum imaging inverse problem: Bayesian regularized non-negative least squares
Multi-echo T 2 magnetic resonance images contain information about the distribution of T 2
relaxation times of compartmentalized water, from which we can estimate relevant brain …
relaxation times of compartmentalized water, from which we can estimate relevant brain …