Skeletal muscle alterations in patients with acute Covid‐19 and post‐acute sequelae of Covid‐19
Skeletal muscle‐related symptoms are common in both acute coronavirus disease (Covid)‐
19 and post‐acute sequelae of Covid‐19 (PASC). In this narrative review, we discuss …
19 and post‐acute sequelae of Covid‐19 (PASC). In this narrative review, we discuss …
[HTML][HTML] The MIC-1/GDF15-GFRAL pathway in energy homeostasis: implications for obesity, cachexia, and other associated diseases
MIC-1/GDF15 is a stress response cytokine and a distant member of the transforming growth
factor beta (TGFb) superfamily, with no close relatives. It acts via a recently identified …
factor beta (TGFb) superfamily, with no close relatives. It acts via a recently identified …
Clinical review: intensive care unit acquired weakness
G Hermans, G Van den Berghe - Critical care, 2015 - Springer
A substantial number of patients admitted to the ICU because of an acute illness,
complicated surgery, severe trauma, or burn injury will develop a de novo form of muscle …
complicated surgery, severe trauma, or burn injury will develop a de novo form of muscle …
Sarcopenia: assessment of disease burden and strategies to improve outcomes
I Liguori, G Russo, L Aran, G Bulli, F Curcio… - … interventions in aging, 2018 - Taylor & Francis
Life expectancy is increasing worldwide, with a resultant increase in the elderly population.
Aging is characterized by the progressive loss of skeletal muscle mass and strength–a …
Aging is characterized by the progressive loss of skeletal muscle mass and strength–a …
The GDF15-GFRAL pathway in health and metabolic disease: friend or foe?
GDF15 is a cell activation and stress response cytokine of the glial cell line–derived
neurotrophic factor family within the TGF-β superfamily. It acts through a recently identified …
neurotrophic factor family within the TGF-β superfamily. It acts through a recently identified …
The role of GDF15 as a myomitokine
Growth differentiation factor 15 (GDF15) is a cytokine best known for affecting systemic
energy metabolism through its anorectic action. GDF15 expression and secretion from …
energy metabolism through its anorectic action. GDF15 expression and secretion from …
GDF15, an emerging key player in human aging
M Conte, C Giuliani, A Chiariello, V Iannuzzi… - Ageing research …, 2022 - Elsevier
Abstract Growth differentiation factor 15 (GDF15) is recently emerging not only as a stress-
related mitokine, but also as a key player in the aging process, being one of the most up …
related mitokine, but also as a key player in the aging process, being one of the most up …
Biomarkers in sarcopenia: a multifactorial approach
F Curcio, G Ferro, C Basile, I Liguori, P Parrella… - Experimental …, 2016 - Elsevier
The slow and continuous loss of muscle mass that progresses with aging is defined as
“sarcopenia”. Sarcopenia represents an important public health problem, being closely …
“sarcopenia”. Sarcopenia represents an important public health problem, being closely …
Intensive care unit-acquired weakness: not just another muscle atrophying condition
H Lad, TM Saumur, MS Herridge… - International journal of …, 2020 - mdpi.com
Intensive care unit-acquired weakness (ICUAW) occurs in critically ill patients stemming from
the critical illness itself, and results in sustained disability long after the ICU stay. Weakness …
the critical illness itself, and results in sustained disability long after the ICU stay. Weakness …
mTORC1 underlies age‐related muscle fiber damage and loss by inducing oxidative stress and catabolism
Aging leads to skeletal muscle atrophy (ie, sarcopenia), and muscle fiber loss is a critical
component of this process. The mechanisms underlying these age‐related changes …
component of this process. The mechanisms underlying these age‐related changes …