Unlocking exosome-based theragnostic signatures: deciphering secrets of ovarian cancer metastasis

S Mukherjee, S Nag, N Mukerjee, S Maitra… - ACS …, 2023 - ACS Publications
Ovarian cancer (OC) is a common gynecological cancer worldwide. Unfortunately, the lack
of early detection methods translates into a substantial cohort of women grappling with the …

miRNA-148b and its role in various cancers

N Dorraki, ZN Ghale-Noie, NS Ahmadi, V Keyvani… - …, 2021 - Taylor & Francis
miRNA-148b belongs to the family miR-148/-152, with significant differences in nonseed
sequences, which can target diverse mRNA molecules. Reportedly, it may undergo …

[HTML][HTML] Stromal POSTN induced by TGF-β1 facilitates the migration and invasion of ovarian cancer

H Yue, W Li, R Chen, J Wang, X Lu, J Li - Gynecologic oncology, 2021 - Elsevier
Objective Periostin (POSTN) overexpression observed in various cancer types is correlated
with metastasis and tumor progression. However, its effect on the crosstalk between ovarian …

[HTML][HTML] Tumor-derived extracellular vesicles promote activation of carcinoma-associated fibroblasts and facilitate invasion and metastasis of ovarian cancer by …

Y Cui, D Wang, M Xie - Frontiers in cell and developmental …, 2021 - pmc.ncbi.nlm.nih.gov
Ovarian cancer (OC) is a lethal gynecological malignancy. Extracellular vesicles (EVs) are
crucial media in cell-to-cell communication by carrying microRNAs (miRs). The current study …

Cancer-associated fibroblast mimetic AIE probe for precision imaging-guided full-cycle management of ovarian cancer surgery

J Dai, H Ouyang, S Wei, B Chen, X Dong, J Hu… - Analytical …, 2023 - ACS Publications
Fluorescence imaging can improve surgical accuracy in ovarian cancer, but a high signal-to-
noise ratio is crucial for tiny metastatic cancers. Meanwhile, intraoperative fluorescent …

Ct-OATP1B3 promotes high-grade serous ovarian cancer metastasis by regulation of fatty acid beta-oxidation and oxidative phosphorylation

Y Huang, Y Du, Y Zheng, C Wen, H Zou, J Huang… - Cell Death & …, 2022 - nature.com
High-grade serous ovarian cancer (HGSOC) is the most lethal gynecologic malignancy
mainly due to its extensive metastasis. Cancer-type organic anion transporting polypeptide …

Laminins in tumor-derived exosomes upregulated by ETS1 reprogram omental macrophages to promote omental metastasis of ovarian cancer

H Li, C Zeng, C Shu, Y Cao, W Shao, M Zhang… - Cell death & …, 2022 - nature.com
Tumor-derived exosomes participate in omental metastatic colonization of ovarian cancer by
inducing an adaptive response in the tumor microenvironment. However, cell–cell …

[68Ga]Ga-FAPI-04 PET/CT in the evaluation of epithelial ovarian cancer: comparison with [18F]F-FDG PET/CT

J Chen, K Xu, C Li, Y Tian, L Li, B Wen, C He… - European Journal of …, 2023 - Springer
Purpose To compare the efficacy of [68Ga] Ga-FAPI-04 PET/CT in primary or recurrent
tumors and metastatic lesions of epithelial ovarian cancer (EOC) with that of fluorine-18 …

PINK1-PTEN axis promotes metastasis and chemoresistance in ovarian cancer via non-canonical pathway

F Zheng, J Zhong, K Chen, Y Shi, F Wang… - Journal of Experimental …, 2023 - Springer
Background Ovarian cancer is commonly associated with a poor prognosis due to
metastasis and chemoresistance. PINK1 (PTEN-induced kinase 1) is a serine/threonine …

A comparative analysis of 2D and 3D experimental data for the identification of the parameters of computational models

M Cortesi, D Liu, C Yee, DJ Marsh, CE Ford - Scientific Reports, 2023 - nature.com
Computational models are becoming an increasingly valuable tool in biomedical research.
Their accuracy and effectiveness, however, rely on the identification of suitable parameters …