Immune checkpoint inhibitors in the treatment of HCC

C Donisi, M Puzzoni, P Ziranu, E Lai, S Mariani… - Frontiers in …, 2021 - frontiersin.org
Hepatocellular carcinoma (HCC) is the typical inflammation-induced neoplasia. It often
prospers where a chronic liver disease persists, thus leading a strong rationale for immune …

Lenvatinib for hepatocellular carcinoma: a literature review

T Hatanaka, A Naganuma, S Kakizaki - Pharmaceuticals, 2021 - mdpi.com
Lenvatinib, which is an oral multikinase inhibitor, showed non-inferiority to the sorafenib in
terms of overall survival (OS) and a higher objective response rate (ORR) and better …

The systemic inflammatory response identifies patients with adverse clinical outcome from immunotherapy in hepatocellular carcinoma

A Muhammed, CAM Fulgenzi, S Dharmapuri, M Pinter… - Cancers, 2021 - mdpi.com
Simple Summary The investigation of predictive and prognostic markers is pivotal in patients
affected by hepatocellular carcinoma treated with immune-checkpoint-inhibitors …

The role of prognostic nutritional index for clinical outcomes of gastric cancer after total gastrectomy

Z Xishan, Z Ye, M Feiyan, X Liang, W Shikai - Scientific Reports, 2020 - nature.com
The purpose of this article is to evaluate the relationship between the nutrition-based
microenvironment and clinicopathological information for gastric cancer patients and to …

Immunonutritive scoring in patients with hepatocellular carcinoma undergoing transarterial chemoembolization: prognostic nutritional index or controlling nutritional …

L Müller, F Hahn, A Mähringer-Kunz, F Stoehr… - Frontiers in …, 2021 - frontiersin.org
Objectives The Prognostic Nutritional Index (PNI) and Controlling Nutritional Status
(CONUT) score are immunonutritive scoring systems with proven predictive ability in various …

Introducing immunotherapy for advanced hepatocellular carcinoma patients: Too early or too fast?

E Lai, G Astara, P Ziranu, A Pretta, M Migliari… - Critical Reviews in …, 2021 - Elsevier
Advanced hepatocellular carcinoma (HCC) is the most frequent liver cancer. Immunotherapy
has been explored in this disease in order to improve survival outcomes. Nowadays …

Biomarkers in hepatobiliary cancers: what is useful in clinical practice?

A Boilève, M Hilmi, M Delaye, A Tijeras-Raballand… - Cancers, 2021 - mdpi.com
Simple Summary In oncology, a new era has emerged in the last ten years with the
development of targeted and immune therapies. In hepatocellular carcinoma (HCC), several …

Prognostic significance of psoas muscle index in male hepatocellular carcinoma patients treated with immune checkpoint inhibitors and tyrosine kinase inhibitors

N Luo, H Li, Y Luo, P Hu, L Liang, R Zhang… - Human Vaccines & …, 2023 - Taylor & Francis
Currently, the relationship between nutritional indices and the prognosis of hepatocellular
carcinoma (HCC) patients treated with immune checkpoint inhibitors (ICIs) and tyrosine …

Role of the prognostic nutritional index in predicting survival in advanced hepatocellular carcinoma treated with atezolizumab plus bevacizumab

M Persano, M Rimini, T Tada, G Suda, S Shimose… - Oncology, 2023 - karger.com
Introduction: The prognostic nutritional index (PNI) is a multiparametric score introduced by
Onodera based on the blood levels of lymphocytes and albumin in patients with …

Clinical value of prognostic nutritional index in prediction of the presence and severity of neonatal sepsis

T Li, M Qi, G Dong, X Li, Z Xu, Y Wei… - Journal of …, 2021 - Taylor & Francis
Purpose The prognostic nutritional index (PNI) is a common indicator of nutritional and
inflammatory status and is associated with various diseases such as cancer, cardiovascular …