Abstract p38 kinases are members of the mitogen-activated protein kinases (MAPK) with
established contribution to a wide range of signaling pathways and different biological …

All organisms and cells respond to various stress conditions such as environmental,
metabolic, or pathophysiological stress by generally upregulating, among others, the …

Alzheimer's disease (AD) is the most common neurodegenerative disease and is
characterized by neurofibrillary tangles (NFTs) composed of Tau protein. α-Lipoic acid (LA) …

α-Crystallins are key members of the superfamily of small heat shock proteins that have
been studied in detail in the ocular lens. Recently, novel functions for α-crystallins have …

Background αB-crystallin, once thought to be a lenticular protein, is ubiquitous and has
critical roles in several cellular processes that are modulated by phosphorylation. Serine …

HSPB4 and HSPB5 (α-crystallins) have shown increasing promise as neuroprotective
agents, demonstrating several anti-apoptotic and protective roles in disorders such as …

Objective Dendrobium nobile is a genuine Chinese medicine. Dendrobium nobile Lindl.
alkaloids (DNLA) protects against CCl 4-induced acute liver injury. This study used RNA …

HSPB5 or alpha B-crystallin (CRYAB), originally identified as lens protein, is one of the most
widespread and represented of the human small heat shock proteins (sHSPs). It is greatly …

Abstract Ethnopharmacological relevance Qishen Granule (QSG) is a prevailing traditional
Chinese medicine formula that displays impressive cardiovascular protection in clinical …

The small heat shock protein αB-crystallin (CRYAB) has been implicated in multiple
sclerosis (MS) pathogenesis. Earlier studies have indicated that CRYAB inhibits …