TFOS DEWS II tear film report

MDP Willcox, P Argüeso, GA Georgiev, JM Holopainen… - The ocular …, 2017 - Elsevier
The members of the Tear Film Subcommittee reviewed the role of the tear film in dry eye
disease (DED). The Subcommittee reviewed biophysical and biochemical aspects of tears …

Biochemistry of human tear film: A review

S Masoudi - Experimental eye research, 2022 - Elsevier
The precorneal tear film is a complex mixture of proteins, lipids, metabolites, and electrolytes
with different structures and functionalities. Sustainable production of each tear component …

[HTML][HTML] The TFOS International Workshop on Contact Lens Discomfort: report of the contact lens interactions with the tear film subcommittee

JP Craig, MDP Willcox, P Argüeso… - … & visual science, 2013 - iovs.arvojournals.org
The aim of the subcommittee report was to review published evidence describing tear film
changes secondary to contact lens wear and to examine the evidence for associations …

An eye on the dog as the scientist's best friend for translational research in ophthalmology: focus on the ocular surface

L Sebbag, JP Mochel - Medicinal Research Reviews, 2020 - Wiley Online Library
Preclinical animal studies provide valuable opportunities to better understand human
diseases and contribute to major advances in medicine. This review provides a …

Biocompatibility of antimicrobial melimine lenses: rabbit and human studies

D Dutta, J Ozkan, MDP Willcox - Optometry and Vision Science, 2014 - journals.lww.com
Purpose Covalent immobilization of antimicrobial peptide melimine onto contact lenses can
produce broad-spectrum antimicrobial lenses. The purpose of this study was to investigate …

Tear fluid protein biomarkers

J You, MD Willcox, MC Madigan, V Wasinger… - Advances in clinical …, 2013 - Elsevier
The tear film covers and protects the ocular surface. It contains various molecules including
a large variety of proteins. The protein composition of the tear fluid can change with respect …

[HTML][HTML] Biophysical properties of tear film lipid layer I. Surface tension and surface rheology

X Xu, G Li, YY Zuo - Biophysical Journal, 2022 - cell.com
Tear film lipid layer (TFLL) is the outmost layer of the tear film. It plays a crucial role in
stabilizing the tear film by reducing surface tension and retarding evaporation of the …

[HTML][HTML] Strain heterogeneity, cooccurrence network, taxonomic composition and functional profile of the healthy ocular surface microbiome

Y Kang, S Lin, X Ma, Y Che, Y Chen, T Wan, D Zhang… - Eye and Vision, 2021 - Springer
Background There is growing evidence indicating that the microbial communities that dwell
on the human ocular surface are crucially important for ocular surface health and disease …

[HTML][HTML] Ion channels in dry eye disease

N Ashok, P Khamar, S D'Souza, M Gijs… - Indian Journal of …, 2023 - journals.lww.com
Dry eye disease (DED) which affects millions of people worldwide is an ocular surface
disease that is strongly associated with pain, discomfort, and visual disturbances. Altered …

[HTML][HTML] The noninflammatory phenotype of neutrophils from the closed-eye environment: a flow cytometry analysis of receptor expression

M Gorbet, C Postnikoff, S Williams - Investigative ophthalmology & …, 2015 - arvojournals.org
Purpose: In the closed-eye environment (during sleep), there is an influx of neutrophils into
the tear film, and the phenotype of these cells has yet to be characterized. This study was …