Background In this so-called treat-all era, antiretroviral therapy (ART) interruptions contribute
to an increasing proportion of HIV infections and deaths. Many strategies to improve …

Introduction The 17 sustainable development goals (SDGs (UN, 2015)) reach far beyond the
eight millennium development goals (UN, 2009) in emphasizing the inextricable …

LILIAN, Rivka R. et al. Baseline CD4 and mortality trends in the South African human
immunodeficiency virus programme: Analysis of routine data. South. Afr. j. HIV …

Modelling complex real-world situations such as infectious diseases, geological
phenomena, and biological processes can present a dilemma: the computer model (referred …

Abstract Background Evidence-based interventions (EBIs) often address normative
behaviors. If a behavior is also common among clinicians, they may be skeptical about the …

Objective Despite widespread uptake, only half of sub-Saharan African countries have fully
implemented the World Health Organization's 'treat all'policy, hindering achievement of …

Introduction The Temprano and START trials provided evidence to support early ART
initiation recommendations. We projected long-term clinical and economic outcomes of …

In September 2015, the World Health Organization (WHO) released updated antiretroviral
treatment guidelines which included recommendations that preexposure prophylaxis (PrEP) …

Background Uganda changed its antiretroviral therapy guidelines in 2014, increasing the
CD4 threshold for antiretroviral therapy initiation from 350 cells/μl to 500 cells/μl. We …

BACKGROUND South Africa has the highest HIV burden in the world. Clinical care
guidelines for HIV testing, treatment, monitoring and infant feeding have evolved in recent …