Triple negative breast cancer: a review of present and future diagnostic modalities

SA Dass, KL Tan, R Selva Rajan, NF Mokhtar… - Medicina, 2021 - mdpi.com
Triple-negative breast cancer (TNBC) is an aggressive breast type of cancer with no
expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal …

Phase separation drives decision making in cell division

X Liu, X Liu, H Wang, Z Dou, K Ruan, DL Hill… - Journal of Biological …, 2020 - ASBMB
Liquid–liquid phase separation (LLPS) of biomolecules drives the formation of subcellular
compartments with distinct physicochemical properties. These compartments, free of lipid …

The Hippo pathway effector YAP promotes ferroptosis via the E3 ligase SKP2

WH Yang, CC Lin, J Wu, PY Chao, K Chen… - Molecular Cancer …, 2021 - AACR
Ferroptosis is a new form of regulated cell death resulting from the accumulation of lipid-
reactive oxygen species. A growing number of studies indicate ferroptosis as an important …

[HTML][HTML] Statistics and network-based approaches to identify molecular mechanisms that drive the progression of breast cancer

MS Alam, MM Rahaman, A Sultana, G Wang… - Computers in Biology …, 2022 - Elsevier
Breast cancer (BC) is one of the most malignant tumors and the leading cause of cancer-
related death in women worldwide. So, an in-depth investigation on the molecular …

Inhibition of NADPH oxidase-ros signal using hyaluronic acid nanoparticles for overcoming radioresistance in cancer therapy

L Zhu, Y Zhao, T Liu, M Chen, WP Qian, B Jiang… - ACS …, 2022 - ACS Publications
Upregulation of NADPH oxidases (NOXs) in cancer cells leads to chronic increase in
intracellular reactive oxygen species (ROS) and adaptation to a high ROS level for cell …

Development and validation of TACE refractoriness-related diagnostic and prognostic scores and characterization of tumor microenvironment infiltration in …

Q He, J Yang, Y Jin - Frontiers in immunology, 2022 - frontiersin.org
Background Transcatheter arterial chemoembolization LIHC, Liver hepatocellular
carcinoma;(TACE) is a valid therapeutic method for hepatocellular carcinoma (HCC) …

TTK inhibition increases cisplatin sensitivity in high-grade serous ovarian carcinoma through the mTOR/autophagy pathway

G Qi, H Ma, Y Li, J Peng, J Chen, B Kong - Cell Death & Disease, 2021 - nature.com
High-grade serous ovarian cancer (HGSOC) is the most lethal gynecological malignancy.
However, the molecular mechanisms underlying HGSOC development, progression …

Short-term CDK4/6 inhibition radiosensitizes estrogen receptor–positive breast cancers

AM Pesch, NH Hirsh, BC Chandler… - Clinical Cancer …, 2020 - AACR
Abstract Purpose: Cyclin-dependent kinase 4/6 (CDK4/6) inhibitors have improved
progression-free survival for metastatic, estrogen receptor–positive (ER+) breast cancers …

Immune-related biomarkers predict the prognosis and immune response of breast cancer based on bioinformatic analysis and machine learning

X Zheng, H Ma, Y Dong, M Fang, J Wang… - Functional & Integrative …, 2023 - Springer
Breast cancer (BC) is the malignancy with the highest mortality rate among women,
identification of immune-related biomarkers facilitates precise diagnosis and improvement of …

An integrated ensemble learning technique for gene expression classification and biomarker identification from RNA-seq data for pancreatic cancer prognosis

G JagadeeswaraRao, A Sivaprasad - International Journal of Information …, 2024 - Springer
Abstract Machine learning (ML) models are used in the interdisciplinary field of bio-ML to
solve biological challenges. The diagnosis and treatment of cancer can benefit from the …