Transcription factors as readers and effectors of DNA methylation

H Zhu, G Wang, J Qian - Nature Reviews Genetics, 2016 - nature.com
Recent technological advances have made it possible to decode DNA methylomes at single-
base-pair resolution under various physiological conditions. Many aberrant or differentially …

Through the looking-glass-Recent developments in reflectometry open new possibilities for biosensor applications

P Fechner, G Gauglitz, G Proll - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
Label-free biosensing has developed from niche application to state of the art biosensing
technique throughout the past decades. The reason for the raise of acceptance for this …

[HTML][HTML] Kinetics and interaction studies of anti-tetraspanin antibodies and ICAM-1 with extracellular vesicle subpopulations using continuous flow quartz crystal …

T Liangsupree, E Multia, P Forssén, T Fornstedt… - Biosensors and …, 2022 - Elsevier
Continuous flow quartz crystal microbalance (QCM) was utilized to study binding kinetics
between EV subpopulations (exomere-and exosome-sized EVs) and four affinity ligands …

In Vivo Detection and Absolute Quantification of a Secreted Bacterial Factor from Skin Using Molecularly Imprinted Polymers in a Surface Plasmon Resonance …

G Ertürk Bergdahl, T Andersson, M Allhorn… - ACS …, 2019 - ACS Publications
In this study, a surface plasmon resonance (SPR) biosensor was developed for the detection
and quantification of a secreted bacterial factor (RoxP) from skin. A molecular imprinting …

Applications in high-content functional protein microarrays

CD Moore, OZ Ajala, H Zhu - Current opinion in chemical biology, 2016 - Elsevier
Highlights•Human proteome microarrays have been developed.•Unbiased, high-throughput
platform for discovery-oriented biology.•Useful for characterization of protein binding …

Development of a Molecular Imprinting-Based Surface Plasmon Resonance Biosensor for Rapid and Sensitive Detection of Staphylococcus aureus Alpha Hemolysin …

T Andersson, A Bläckberg, R Lood… - Frontiers in cellular and …, 2020 - frontiersin.org
Stapylococcus aureus is a common infectious agent in eg sepsis, associated with both high
mortality rates and severe long-term effects. The cytolytic protein α-hemolysin has …

Two decades of arrayed imaging reflectometry for sensitive, high-throughput biosensing

G Kosoy, BL Miller - Biosensors, 2023 - mdpi.com
Arrayed imaging reflectometry (AIR), first introduced in 2004, is a thin-film interference
sensor technique that optimizes optical properties (angle of incidence, polarization …

A single-domain antibody library based on a stability-engineered human VH3 scaffold

NJ Lee, M Jung, HY Yang, H Shim - Scientific Reports, 2024 - nature.com
Using conventional immunoglobulin G (IgG) molecules as therapeutic agents presents
several well-known disadvantages owing to their large size and structural complexity …

Direct detection of bacteremia by exploiting host-pathogen interactions of lipoteichoic acid and lipopolysaccharide

JZ Kubicek-Sutherland, DM Vu, A Noormohamed… - Scientific reports, 2019 - nature.com
Bacteremia is a leading cause of death in sub-Saharan Africa where childhood mortality
rates are the highest in the world. The early diagnosis of bacteremia and initiation of …

Measuring ligand binding kinetics to membrane proteins using virion nano-oscillators

G Ma, GD Syu, X Shan, B Henson… - Journal of the …, 2018 - ACS Publications
Membrane proteins play vital roles in cellular signaling processes and serve as the most
popular drug targets. A key task in studying cellular functions and developing drugs is to …