Coevolution of humans and malaria parasites has generated an intricate balance between
the immune system of the host and virulence factors of the parasite, equilibrating maximal …

Systemic sclerosis (SSc) is a connective tissue disease characterized by extensive fibrosis
of the skin and internal organs, associated with vasculopathy and autoimmune features …

Although infection with the dengue virus (DENV) causes severe dengue, it causes a mild
self-limiting illness in the majority of individuals. There is emerging evidence that an …

Monocytes are innate immune cells essential for host protection against malaria. Upon
activation, monocytes function to help reduce parasite burden through phagocytosis …

Infection with Plasmodium vivax results in strong activation of monocytes, which are
important components of both the systemic inflammatory response and parasite control. The …

There are seven known species of Plasmodium spp. that can infect humans. The human
host can mount a complex network of immunological responses to fight infection and one of …

BACKGROUND. Inflammation and monocytes are thought to be important to human malaria
pathogenesis. However, the relationship of inflammation and various monocyte functions to …

The Fulani ethnic group from West Africa is relatively better protected against Plasmodium
falciparum malaria as compared to other sympatric ethnic groups, such as the Dogon …

Monocytes are plastic heterogeneous immune cells involved in host-parasite interactions
critical for malaria pathogenesis. Human monocytes have been subdivided into three …

Background Severe malarial anaemia (SMA) is a major life-threatening complication of
paediatric malaria. Protracted production of pro-inflammatory cytokines promoting …